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3 factors may lower depression risk, new evidence suggests

New studies suggest lifestyle and treatment choices may reduce depression risk—GLP-1 meds like Ozempic, citrus fruits, and regular exercise all show promising protective effects.

  • Depression affects a large proportion of the global population, but there are ways to mitigate the risk of this mental health condition.
  • Recent evidence builds on the role that elements of diet, physical activity, and certain medications may play in depression risk.
  • One study from February 2025, for instance, suggests that people who take glucagon-like peptide-1 receptor agonist medication like Ozempic to treat diabetes have a lower depression risk than peers taking other types of drugs for this metabolic condition.
  • Another study from November 2024 indicates that eating oranges and other citrus fruits daily may help reduce depression risk.
  • Finally, research from March 2025 indicates that undertaking regular moderate-to-vigorous exercise could help lower the risk for neuropsychiatric diseases, including depression.

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NeoHealth® ID 37776 · updated 5/29/2025