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Calming the acid: Pharmacotherapeutic approaches to gastro-oesophageal reflux disorder

Gastro-oesophageal reflux disease (GORD) is a chronic disorder where gastric contents, including gastric acid, pepsin and food, enter the oesophagus, which leads to irritation and potential erosion.

In this review, the broad medication classes used for GORD treatment in South Africa are discussed, including the first-line proton pump inhibitors, histamine-2-receptor antagonists, antacids, and alginate-based treatments.

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NeoHealth® ID 38916 · updated 1/20/2026