Articles
Carboprost versus Oxytocin as the First-Line Treatment of Primary Postpartum Haemorrhage (COPE)
Can carboprost beat oxytocin? New trial compares PPH treatments, side effects & cost-effectiveness.
Excessive bleeding after childbirth (postpartum haemorrhage, PPH) affects 5% of births and causes 75 000 maternal deaths worldwide annually. It is the leading cause of direct maternal deaths globally and continues to be a major cause of mortality in the UK. Oxytocin is the standard first-line treatment for atonic PPH. The PPH rate is increasing, and this may be partially related to the overuse of oxytocics in labour.
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