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Catheter Ablation vs Drug Therapy in Patients With Atrial Fibrillation and Nonmodifiable Recurrence Risk Factors

Are non-modifiable recurrence risk factors associated with differences in the benefit of catheter ablation compared with drug therapy in patients with atrial fibrillation?

A sub-analysis of the CABANA trial found that catheter ablation significantly reduced the risk of death, disabling stroke, or cardiac arrest in atrial fibrillation (AF) patients with fewer than three non-modifiable recurrence risk factors. However, it showed no significant benefit for those with three or more risk factors.

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NeoHealth® ID 38437 · updated 9/5/2025