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Common Sugar Substitute May Affect Brain and Blood Vessel Health

New research links erythritol to increased vascular risks (clotting, heart disease, stroke), even from small amounts, prompting experts to advise limiting or avoiding it.

  • Recent studies suggest a connection between higher levels of erythritol — a popular sweetener — in the blood and an increased risk of vascular health issues, such as blood clotting, heart disease, and stroke.
  • New cellular research adds supporting evidence that the amount of erythritol in just 1 serving of a beverage could harm brain and blood vessel health.
  • Experts advise limiting or avoiding erythritol and opting for what seem to be safer noncaloric sweeteners, such as stevia and monk fruit extract.

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NeoHealth® ID 38065 · updated 6/5/2025