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Diphtheria situational report (week 48 of 2025)

Respiratory diphtheria is a vaccine-preventable illness caused by toxigenic C. diphtheriae (and, more rarely, C. ulcerans or C. pseudotuberculosis) and can occur in persons of all ages.

Between 01 January 2024 and 30 November 2025, 81 confirmed cases of respiratory diphtheria, 2 probable respiratory diphtheria cases and 56 asymptomatic carriers of toxigenic C. diphtheriae, detected during contact tracing, have been identified in South Africa. 

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NeoHealth® ID 38863 · updated 12/15/2025