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Menopausal hormone therapy and central nervous system tumors: Danish nested case-control study

Meningiomas are the most common benign tumors of the central nervous system (CNS) and occur more frequently in women, with a female:male ratio of up to 3.5, the greatest ratio being among middle-aged individuals.

Meningiomas are the most common benign tumors of the central nervous system (CNS) and occur more frequently in women, with a female:male ratio of up to 3.5, the greatest ratio being among middle-aged individuals. Conversely, gliomas are the most common malignant CNS tumors, with a 50% higher incidence among men. While the etiology of these tumors is largely unknown and only a few rare risk factors have been established, the sex difference in incidence indicates potential risk factors related to the sex, including exogenous use of female sex hormones.

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NeoHealth® ID 35979 · updated 11/20/2024