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Metabolic Health and Heterogenous Outcomes of Prenatal Interventions

Do preexisting metabolic phenotypes of obesity differentially influence the outcomes of a prenatal lifestyle intervention aimed at reducing excess gestational weight gain?

A study of obese pregnant people found that the metabolically unhealthy obesity (MUO) phenotype was associated with a higher incidence of gestational diabetes and greater infant adiposity, despite having lower gestational weight gain than the metabolically healthy phenotype.

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NeoHealth® ID 38436 · updated 9/5/2025