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Muscle loss from GLP-1 drugs may not be as high as thought.
While past studies show that adults taking a GLP-1 medication can lose between 5-15% of their starting body weight, other research reports that a good portion of that weight loss comes from muscle loss.
A mouse model study suggests that muscle loss from GLP-1 medications may be lower than previously reported. Researchers found that much of the lean mass decrease wasn't from skeletal muscle, but from other tissues like the liver, which shrank by nearly half. This offers new insights into how these drugs affect body composition.
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