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Use of angiotensin receptor – neprilysin inhibitors in heart failure: a paradigm shift

Heart failure is a clinical syndrome responsible for at least one-third of hospitalisations amongst cardiac patients, with escalating mortality and healthcare costs on both public and private health care.

A recently developed pharmacotherapy that inhibits both the angiotensin receptor and the enzyme neprilysin has shown promise in the management of heart failure with reduced ejection fraction.

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NeoHealth® ID 38820 · updated 12/3/2025