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Xpert MTB/RIF Ultra assay for pulmonary tuberculosis and rifampicin resistance in adults and adolescents

A WHO-supported review found Xpert Ultra has high sensitivity (90.7%) and specificity (94.8%) for detecting pulmonary tuberculosis and high accuracy for rifampicin resistance (95.8% sensitivity, 98.3% specificity).

Xpert MTB/RIF Ultra (Xpert Ultra) is a molecular World Health Organization (WHO)‐recommended rapid diagnostic test that simultaneously detects tuberculosis and rifampicin resistance. This review updates a comparative accuracy Cochrane review of Xpert MTB/RIF and Xpert Ultra as Xpert Ultra has replaced Xpert MTB/RIF.

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Drugs mentioned

NeoHealth® ID 38326 · updated 8/12/2025