Aescin/ Diethylamine

Registered South African indications:

• Symptomatic relief of pain associated with superficial soft tissue injuries, such as certain sports injuries
• Temporary relief from the minor pain and stiffness of rheumatism and muscle soreness

Contraindications

• Hypersensitivity to the active ingredient or any of its excipients
• Do not apply to broken skin and excessively raw areas

Cautions

• Breastfeeding
• Eczema
• Skin ulceration
• Skin exposed to therapeutic irradiation

Forms avail. in SA and covered in this monograph: gel

Symptomatic relief of pain associated with superficial soft tissue injuries, such as certain sports injuries
Temporary relief from the minor pain and stiffness of rheumatism and muscle soreness

• Topical (gel): Apply a thin layer to the affected area, as needed several times daily

No information available

Pregnancy 

• FDA Pregnancy Category Not Rated (NR)

Breastfeeding 

• Caution

Renal Impairment 

• No dose adjustment recommended 

Hepatic Impairment 

• No dose adjustment recommended

Elderly 

• No dose adjustment recommended

Skin and Subcutaneous Disorders

• Erythema
• Desquamation
• Urticaria
• Angio-neurotic oedema 

No information available

None routine

Aescin reduces capillary permeability resulting in a decrease of fluid ouflow into the tissue. Diethylamine stops the release of inflammation mediators.

COMBINATION PREPARATIONS

Aescin/ Diethylamine salicylate

Gel (per 100g) 1g/5g

• Reparil gel (Takeda) Originator