Belladonna Tinture (oral)

Contraindications

• Hypersensitivity to the active ingredient or any of its excipients
• Hypersensitivity to anticholinergics
• Breastfeeding
• Severe hepatic impairment
• Severe renal impairment
• Myasthenia gravis or similar syndrome
• Narrow-angle glaucoma
• Gastro-oesophageal reflux disease
• Obstructive gastrointestinal diseases
• Paralytic ileus
• Ulcerative colitis
• Toxic mega colon
• Intestinal motility
• Obstructive uropathy
• Unstable cardiovascular disease

Cautions

• Pregnancy
• Mild to moderate renal impairment
• Mild to moderate hepatic impairment  
• Elderly

Pregnancy

• Caution
• Consider using safer alternatives

Breastfeeding

• Contraindicated
• Belladonna is excreted in breast milk, therefore consider safer alternatives
• Long-term use of belladonna reduces prolactin secretion and might thus, interfere with lactation

Renal impairment

• Mild to moderate: Caution; no information available
  Consider alternative drugs
• Severe: Contraindicated

Hepatic impairment

• Mild to moderate: Caution; no information available
  Consider alternative drugs
• Severe: Contraindicated

Elderly

• Caution; no information available
  Consider alternative drugs

Porphyria Information

• Not yet classified (NC)

Central Nervous System Disorders

• Drowsiness
• Light-headedness
• Dizziness
• Agitation
• Delirium
• Hallucinations
• Amnesia
• Hyperthermia

Cardiovascular Disorders

• Tachycardia

Gastrointestinal Disorders

• Dry mouth

Genitourinary Disorders

• Urinary retention

Skin and Subcutaneous Tissue Disorders

• Dermatitis

Sensory Disorders

• Dry eyes
• Mydriasis 
• Blurred vision

• Antimuscarinic agents
• Anticholinergic agents

Belladonna is an antimuscarinic drug similar to atropine. Several preparations of belladonna have been used for a variety of conditions including the relief of gastrointestinal and urinary tract related smooth muscle spasms.