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DrugsLevel 4 LocalisationS0OTH · LOZEML

Cetylpyridinium

Pyridinium derivativeAntiseptic, Antibacterial

Indications

Registered South African indications:

  • Tonsillitis
  • Laryngitis
  • Oral infections

Cautions

Contraindications

  • Hypersensitivity to the active ingredient or any of its excipients

Cautions

  • Pregnancy
  • Breastfeeding
  • Renal impairment
  • Hepatic impairment

Adult dosage

Forms avail. in SA and covered in this monograph: loz

Tonsillitis
Laryngitis
Oral infections
- Mouth and gum infections

  • Oral (loz): 1 lolly, 3hrly, allow to dissolve slowly in the mouth

Paediatric dosage

See adult dosage


For infants constant supervision is recommended

Special populations

Adverse reactions

Gastrointestinal Disorders

  • Mouth irritation
  • Tongue discolouration

Sensory Disorders

  • Dental discolouration

Interactions

No information available

Monitoring

None routine

Mechanism of action

Cetylpyridinium is a quaternary ammonium with a broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In dental hygiene products, it mediates a protective action against dental plaque and reducing gingivitis.

Dosage forms

  • Other
  • Lozenge

Formulation

Cetylpyridinium chloride is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

Lolly (per lolly) 3mg

  • Goldex Throat lollies (Goldex)

Also available in the following form: Oral rinse.

References

1. https://drive.google.com/drive/folders/1A1mLaLlW4ht_llRRMvabiiT7T_8XNy2O (07/02/1975_Goldex_Goldex_throat lollies) 2. https://www.uptodate.com/contents/cetylpyridinium-drug-information?source=search_result&search=cetylpyridinium&selectedTitle=1~13 **No SPC available *no drugs.com

Brands & products

10 products · stale NAPPI snapshot · refreshed 5/28/2026 · 159 days old

solutionGeneric· 1 product

from R0.78/unit
ProductStrengthPackSchedSEPUnitDisp feeNAPPI
Medi-Keel A Throat Gargle 30 mg/15ml200S1R155.86R0.78R65.81741043017

MowGeneric· 1 product

from R0.87/unit
ProductStrengthPackSchedSEPUnitDisp feeNAPPI
Medi-keel a throat gargle30 mg/15ml100S1R87.01R0.87R41.99741043018

LozGeneric· 8 products

from R4.31/unit
ProductStrengthPackSchedSEPUnitDisp feeNAPPI
Endcol throat5 mg16S1R68.92R4.31R35.73873977009
Cepacol Sore Throat And Cough Relief Discs- mg16S2R78.36R4.90R39.00703260009
Cepacol sore throat and cough relief dis- mg16S2R81.09R5.07R39.94713260009
Medi-keel a honey & lemon12 mg16S1R92.84R5.80R44.00884225004
Medi-keel a black currant12 mg16S1R92.84R5.80R44.00884233007
Medi-keel a menthol12 mg16S1R92.84R5.80R44.00741035006
Cepacol plus original (was cepacaine)10 mg16S1R111.29R6.96R50.39713236019
Cepacol plus blackcurrant (was cepacain10 mg16S1R111.29R6.96R50.39883872004
Trade names (1)
  • Goldex Throat lollies

Medical aid coverage

data not yet integrated
Discovery Health
not yet integrated
  • Comprehensive Series—
  • Executive Plan—
  • KeyCare Series—
  • Priority Series—
  • Saver Series—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

Bonitas Medical Fund
not yet integrated
  • BonClassic—
  • BonComprehensive—
  • BonEssential—
  • BonFit Select—
  • BonSave—
  • BonStart—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

GEMS — Government Employees Medical Scheme
not yet integrated
  • Beryl—
  • Emerald—
  • Onyx—
  • Ruby—
  • Sapphire—
  • Tanzanite One—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

POLMED — Police Medical Aid Scheme
not yet integrated
  • Aquarium Option—
  • Efficiency Option—
  • Marine Option—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

NeoHealth® ID 16115 · updated 7/12/2022