Cetylpyridinium
Indications
Registered South African indications:
- Tonsillitis
- Laryngitis
- Oral infections
Cautions
Contraindications
- Hypersensitivity to the active ingredient or any of its excipients
Cautions
- Pregnancy
- Breastfeeding
- Renal impairment
- Hepatic impairment
Adult dosage
Forms avail. in SA and covered in this monograph: loz
Tonsillitis
Laryngitis
Oral infections
- Mouth and gum infections
- Oral (loz): 1 lolly, 3hrly, allow to dissolve slowly in the mouth
Paediatric dosage
See adult dosage
For infants constant supervision is recommended
Special populations
Pregnancy
Breastfeeding
Renal Impairment
Hepatic Impairment
Elderly
Porphyria Information
Drugs in Sport
- Permitted - No warning
Adverse reactions
Gastrointestinal Disorders
- Mouth irritation
- Tongue discolouration
Sensory Disorders
- Dental discolouration
Interactions
No information available
Monitoring
None routine
Mechanism of action
Cetylpyridinium is a quaternary ammonium with a broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In dental hygiene products, it mediates a protective action against dental plaque and reducing gingivitis.
Dosage forms
- Other
- Lozenge
Formulation
Cetylpyridinium chloride is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication
Lolly (per lolly) 3mg
- Goldex Throat lollies (Goldex)
Also available in the following form: Oral rinse.
References
1. https://drive.google.com/drive/folders/1A1mLaLlW4ht_llRRMvabiiT7T_8XNy2O (07/02/1975_Goldex_Goldex_throat lollies) 2. https://www.uptodate.com/contents/cetylpyridinium-drug-information?source=search_result&search=cetylpyridinium&selectedTitle=1~13 **No SPC available *no drugs.com
Brands & products
10 products · stale NAPPI snapshot · refreshed 5/28/2026 · 159 days oldsolutionGeneric· 1 product
from R0.78/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Medi-Keel A Throat Gargle | 30 mg/15ml | 200 | S1 | R155.86 | R0.78 | R65.81 | 741043017 |
MowGeneric· 1 product
from R0.87/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Medi-keel a throat gargle | 30 mg/15ml | 100 | S1 | R87.01 | R0.87 | R41.99 | 741043018 |
LozGeneric· 8 products
from R4.31/unit| Product | Strength | Pack | Sched | SEP | Unit | Disp fee | NAPPI |
|---|---|---|---|---|---|---|---|
| Endcol throat | 5 mg | 16 | S1 | R68.92 | R4.31 | R35.73 | 873977009 |
| Cepacol Sore Throat And Cough Relief Discs | - mg | 16 | S2 | R78.36 | R4.90 | R39.00 | 703260009 |
| Cepacol sore throat and cough relief dis | - mg | 16 | S2 | R81.09 | R5.07 | R39.94 | 713260009 |
| Medi-keel a honey & lemon | 12 mg | 16 | S1 | R92.84 | R5.80 | R44.00 | 884225004 |
| Medi-keel a black currant | 12 mg | 16 | S1 | R92.84 | R5.80 | R44.00 | 884233007 |
| Medi-keel a menthol | 12 mg | 16 | S1 | R92.84 | R5.80 | R44.00 | 741035006 |
| Cepacol plus original (was cepacaine) | 10 mg | 16 | S1 | R111.29 | R6.96 | R50.39 | 713236019 |
| Cepacol plus blackcurrant (was cepacain | 10 mg | 16 | S1 | R111.29 | R6.96 | R50.39 | 883872004 |
- Goldex Throat lollies
Medical aid coverage
data not yet integrated- Comprehensive Series—
- Executive Plan—
- KeyCare Series—
- Priority Series—
- Saver Series—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- BonClassic—
- BonComprehensive—
- BonEssential—
- BonFit Select—
- BonSave—
- BonStart—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Beryl—
- Emerald—
- Onyx—
- Ruby—
- Sapphire—
- Tanzanite One—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Aquarium Option—
- Efficiency Option—
- Marine Option—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.