Cetylpyridinium Chloride/ Benzyl Alcohol

Registered South African indications:

• Sore throat

Hypersensitivity to the active ingredient or any of the excipients in this combination product

Cetylpyridinium Chloride
Contraindications

• Hypersensitivity to the active ingredient or any of the excipients in this combination product

Cautions

• Pregnancy
• Breastfeeding
• Renal impairment
• Hepatic imapairment
• Prolonged use

Benzyl Alcohol
Contraindications

• Hypersensitivity to the active ingredient or to any of the excipients in this combination product

Cautions

• Children
• Neonates

Additional contraindications for this combination product

• Diabetes mellitus
• Children < 3 years

Forms avail. in SA and covered in this monograph: loz

Sore throat

Cetylpyridinium Chloride/ Benzyl Alcohol
1.47/6.50 (mg)

• Oral (loz): 1 loz, as needed

Not established for use in children below 3 years

Recommendations for this combination product as per highest risk category when comparing individual active ingredients

Pregnancy

• FDA Pregnancy Category Not Rated (NR) (Cetylpyridinium Chloride)

Breastfeeding

• Caution; no information available (Cetylpyridinium Chloride)

Renal Impairment

• Caution; no information available (Cetylpyridinium Chloride)

Hepatic Impairment

• Caution; no information available (Cetylpyridinium Chloride)

Elderly

• No dose adjustment recommended (Cetylpyridinium Chloride, Benzyl Alcohol)

Drugs in Sport

• Permitted - No warning

Hypersensitivity to the active ingredient or any of the excipients in this combination product

Cetylpyridinium Chloride
Gastrointestinal Disorders

• Nausea and vomiting

Sensory Disorders

• Dental discoloration
• Mouth irritation
• Tongue discoloration

Benzyl Alcohol
Central Nervous System Disorders

• Hypoasthesia

No information available

None routine

Cetylpyridinium Chloride
Cetylpyridinium chloride is bactericidal against a wide variety of Gram-positive and Gram-negative bacteria which include haemolytic Streptococcus, Staphylococcus aureus, Escherichia coli and Lactobacillus acidophilus. Fungicidal action has been demonstrated against Monilia albicans, the cause of oral thrush.

Benzyl Alcohol
Benzyl alcohol has local anaesthetic properties.

COMBINATION PREPARATIONS

Cetylpyridinium chloride/Benzyl Alcohol

Lozenges 1.47mg/6.50mg

• Cepacol throat lozenges Blackcurrant flavour (Adcock)
• Cepacol throat lozenges Honey and Lemon flavour (Adcock)
• Cepacol throat lozenges Menthol (Adcock)
• Cepacol throat lozenges Regular (Adcock)