Diphenhydramine/ Mepyramine Maleate

Registered South African indications:

• Allergic and pruritic skin conditions
• Nettle stings, insect bites and jellyfish stings

Registered South African contraindications

• Eczema

South African recommendations

• Renal impairment
• Hepatic impairment
• Elderly
• Application to large areas of the skin

Forms avail. in SA and covered in this monograph: cre

South African registered indications and dosages

Allergic and pruritic skin conditions
Nettle stings, insect bites and jellyfish stings

Diphenhydramine/ Mepyramine maleate
50/50 (mg)

• Topical (cre): Apply to affected area(s), 2-3 times dly

For external use only

No information available

South African recommendations

Not known

South African recommendations

• Caution; no information available

South African recommendations

• Caution; no information available

South African recommendations

• Caution; no information available

Skin and Subcutaneous Tissue Disorders

• Skin sensitisation
• Dermatitis

Others

• Systemic side effects (after topical application of antihistamines to large areas of the skin)

Not known

None routine

Antihistamines diminish or abolish the main actions of histamine in the body.

COMBINATION PREPARATIONS

Diphenhydramine/ Mepyramine maleate

Cream (per 5g) 50mg/50mg

• Histodor (Pharmacare)