Hypromellose Combination

Registered South African indications

• Dry eyes

Contraindications

• Hypersensitivity to the active ingredient or any of its excipients

Cautions

• Pregnancy
• Renal impairment
• Hepatic impairment
• Concomitant use of contact lenses

Forms avail. in SA and covered in this monograph: opd

Dry eyes
-Mucin-deficient
-Aqueous-deficient

Hypromellose/ Povidone/ Glycerine
0.5/0.1/0.2 (%)
Dextran-70/ Hypromellose
1/3 (mg/ml)

• Ophthalmic (opd): Apply 1-2 drops into affected eye(s), as needed

Paed forms avail. in SA and covered in this monograph: opd

Dry eyes
-Mucin-deficient
-Aqueous-deficient

Hypromellose/ Povidone/ Glycerine
0.5/0.1/0.2 (%)
Dextran-70/ Hypromellose
1/3 (mg/ml)

• See adult dosage 

Pregnancy

• FDA Pregnancy Category Not Rated (NR)

Breastfeeding

• Compatible

Renal Impairment

• Caution; no information available

Hepatic Impairment

• Caution; no information available

Elderly

• No dose adjustment recommended

Porphyria Information

• Not porphyrinogenic (NP)

Drugs in Sport

• Permitted - No warning

Sensory Disorders

• Blurred vision
• Crusting of eyelid
• Stinging of eyes
• Itching 
• Excessive watering of the eyes
• Unusual eye secretions
• Redness of the eyes
• Sensitivity to light

No information available

None routine

The dextran and hydroxypropyl methylcellulose polymers mimic the action of conjunctival mucin, helping mucin-deficient states and increasing the ocular retention time in aqueous-deficient states through the adsorption action of the polymers attaching to the ocular surface. The absorption effect is independent of the viscosity thus ensuring a prolonged wetting action with a low viscosity.

Hypromellose Combination is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

COMBINATION PREPARATIONS

Dextran-70/ Hypromellose

Eye drops (per ml) 1mg/3mg

• Tears naturale preservative-free (Alcon) 
• Tears naturale II (Alcon)