Iron Polymaltose

Registered South African indications:

• Iron deficiency
• Anaemia

Contraindications

• Hypersensitivity to the active ingredient or any of its excipients
• Haemochromatosis
• Haemosiderosis

Caution

• Pregnancy
• Renal impairment
• Hepatic impairment

Forms avail. in SA and covered in this monograph: chu, syr

Iron deficiency
Iron deficiency anaemia

• Oral (chu): 100-200mg, dly
• Oral (syr): Initial: 25-50mg, dly; Titrate by 20-25mg; Maintenance: 200mg, dly

Should be taken in divided doses with meals

Paed. forms avail. in SA and covered in this monograph: syr

Iron deficiency
Iron deficiency anaemia

Younger than 6 months

• Oral (syr): 10-25mg, dly

Between 6 months - 2 years

• Oral (syr): 6mg/kg, dly

Between 2 - 5 years

• Oral (syr): 15-50mg, dly

Between 6 - 12 years

• Oral (syr): 25-125mg, dly

Older than 12 years

• See adult dosage

Should be taken in divided doses with meals

Infants with low birth weight or with low iron stores should be initiated on 2mg/kg/day, decreased gradually to 1mg/kg/day

Pregnancy

• Not rated (No information)

Breastfeeding

• Compatible
• Small quantities of unmodified iron polymaltose can pass into the breast milk.  Administration of this product in breastfeeding women is unlikely to cause adverse reactions on the suckling child  

Renal Impairment

• Caution; no dose adjustment recommended

Hepatic Impairment

• Caution; no dose adjustment recommended 

Elderly

• No dose adjustment recommended 

Porphyria  Information

• Not yet classified (NC)

Drugs in Sport

• Permitted - No warning

Central Nervous System Disorders

• Headache
• Lassitude

Gastrointestinal Disorders

• Constipation
• Diarrhoea
• Darkening of stools
• Heartburn
• Abdominal pain
• Nausea and vomiting
• Stomach cramps

• Alpha-lipoic acid
• Antacids
• Bisphosphonate derivatives
• Cefdinir
• Deferiprone
• Dimercaprol
• Dolutegravir
• Eltrombopag
• Entacapone
• Parenteral iron 
• Levodopa
• Levothyroxine
• Methyldopa
• Penicillamine
• Phosphate supplements
• Quinolone anitbiotics
• Tetracycline derivatives
• Trientine

None routine

Iron polymaltose replaces depleted iron stores, and thus replenishes haemoglobin as well as vital iron-containing enzymes necessary for the oxidative processes in living tissues.

Iron polymaltose is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

Tablet chewable 100mg

• Ferrimed ds chew (Takeda)

Syrup (per 5ml) 50mg

• Ferrimed syrup (Takeda)