neobookRx
DrugsLevel 4 LocalisationN/AOTHEML

Malathion (topical)

Cholinesterase inhibitorNot available as a single agent preparation

Cautions

Contraindication

  • Hypersensitivity to the active ingredient or any of its excipients
  • Pregnancy
  • Breastfeeding
  • Children <30 months

Cautions

  • Renal impairment
  • Hepatic impairment
  • Exposure to eyes, mucous membrane or denuded skin
  • Flammable

Special populations

Pregnancy

  • Contraindicated

Breastfeeding

Renal Impairment

Hepatic Impairment

Elderly

Porphyria Information

Adverse reactions

Skin and Subcutaneous Tissue Disorders

  • Burning
  • Pruritis
  • Irritation

Interactions

No information available

Mechanism of action

Malathion is an organophosphate insecticide used in the treatment of head and pubic pediculosis and scabies. Malathion exerts its action on the nervous system of the lice by irreversibly inhibiting the activity of cholinesterase, hence allowing acetylcholine accumulation in synapse that results in the death of the lice.

Dosage forms

  • Other

References

1. Pharmacologist: Dr Ahmed Abulfathi 1.1 Martindale 1.2 Afritox 1.3 PubChem, US National Library of Medicines 2. https://www.drugs.com/mtm/malathion-topical.html 3. NAPOS: The Drug Database for Acute Porphyria: Malathion; Accessed online 12 April 2019 [http://www.drugs-porphyria.org/languages/UnitedKingdom/s3.php?l=gbr&atc_code=P03AX03]

Medical aid coverage

data not yet integrated
Discovery Health
not yet integrated
  • Comprehensive Series—
  • Executive Plan—
  • KeyCare Series—
  • Priority Series—
  • Saver Series—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

Bonitas Medical Fund
not yet integrated
  • BonClassic—
  • BonComprehensive—
  • BonEssential—
  • BonFit Select—
  • BonSave—
  • BonStart—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

GEMS — Government Employees Medical Scheme
not yet integrated
  • Beryl—
  • Emerald—
  • Onyx—
  • Ruby—
  • Sapphire—
  • Tanzanite One—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

POLMED — Police Medical Aid Scheme
not yet integrated
  • Aquarium Option—
  • Efficiency Option—
  • Marine Option—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

NeoHealth® ID 15803 · updated 7/12/2022