Mephenesin
Cautions
Contraindications
- Hypersensitivity to the active ingredient or to any of its excipients
- Hepatic impairment
Cautions
- Pregnancy
- Breastfeeding
- Renal impairment
- Elderly
- May impair ability to drive and operate machinery
Special populations
Pregnancy
- Caution
- Use of mephenesin during pregnancy is not recommended as available evidence is inadequate to determine foetal risk
Breastfeeding
- Caution; not recommended
- Use of mephenesin during breastfeeding is not recommended as available evidence is inadequate to determine infant risk
Renal Impairment
- Caution; no information available
Data unavailable to asses risk-benefit, therefore use is not recommended
Hepatic Impairment
Elderly
- Caution; no dose adjustment recommended
Avoid use
Porphyria Information
Adverse reactions
Central Nervous System Disorders
- Dizziness
- Drowsiness
Gastrointestinal Disorders
- Nausea and vomiting
Skin and Subcutaneous Tissue Disorders
- Urticaria
- Pruritus
- Rash
Immune, Blood and Lymphatic System Disorders
- Fever
Sensory Disorders
- Blurred vision
Interactions
No information available
Mechanism of action
Mephenesin is a centrally acting skeletal muscle relaxant used for the symptomatic treatment of painful muscle spasm. Its clinical usefulness is limited by its short duration of action and does not relieve the spasticity associated with chronic neurological disorders.
Dosage forms
- Other
References
1. Pharmacologist: Dr Ahmed Abulfathi 1.1 Martindale 1.2 PubChem 1.3 Sinha JN et al. Jap. J. Pharmac. 1118, 48-53 (1968) 1.4 Spasmend PIL 2. NAPOS: The Drug Database for Acute Porphyria: Mephenesin; Accessed online 01 Apr 2019 [http://www.drugs-porphyria.org/languages/UnitedKingdom/s3.php?l=gbr&atc_code=M03BX06]
Medical aid coverage
data not yet integrated- Comprehensive Series—
- Executive Plan—
- KeyCare Series—
- Priority Series—
- Saver Series—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- BonClassic—
- BonComprehensive—
- BonEssential—
- BonFit Select—
- BonSave—
- BonStart—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Beryl—
- Emerald—
- Onyx—
- Ruby—
- Sapphire—
- Tanzanite One—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Aquarium Option—
- Efficiency Option—
- Marine Option—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.