Noscapine

Registered South African indications:

• Cough

Contraindications

• Hypersensitivity to noscapine of any of its excipients
• Women of childbearing age
  - Pregnancy
  - Breastfeeding

Cautions

• Renal impairment
• Hepatic impairment
• Elderly

Forms avail. in SA and covered in this monograph: syr

Non-productive cough

• Oral (syr): 25-50mg, 8hrly, depending on severity

Paed. forms avail. in SA and covered in this monograph: syr

Non-productive cough

Younger than 4 months

• Not established for use

Between 4-12 months

• Oral (syr):  2.5-7.5mg, 8hrly

Between 1-7 years

• Oral (syr): 7.5-12.5mg, 8hrly 

Between 7-12 years

• Oral (syr): 12.5-25mg, 8hrly 

Older than 12 years

• See adult dosage

Pregnancy

• Contraindicated
• Use is contraindicated in women if childbearing age

Breastfeeding

• Contraindicated
• Use is contraindicated in women if childbearing age

Renal Impairment

• Caution; no information available

Hepatic Impairment

• Caution; no information available

Elderly

• Caution; no information available

Porphyria Information

• Possibly porphyrinogenic (PSP)

Drugs in Sport

• Permitted - No warnings 

Central Nervous System Disorders

• Drowsiness
• Dizziness
• Headache

Respiratory Disorders

• Allergic rhinitis

Gastrointestinal Disorders

• Nausea

Skin and Subcutaneous Tissue Disorders

• Skin rash

Sensory Disorders

• Conjunctivitis

No information available

None routine

Noscapine is a non-narcotic alkaloid derived from the opium poppy that exerts its antitussive effects via activation of sigma opioid receptors.

Syrup (per 5ml) 25mg

• Nitepax (Pharmacare) originator