neobookRx
DrugsLevel 4 LocalisationN/AOTHEML

Sorbimacrogol (oral)

SurfactantNot available as a single agent preparation

Cautions

Contraindications

  • Hypersensitivity to the active ingredient or any of its excipients
  • Renal impairment
  • Hepatic impairment

Cautions

  • Pregnancy
  • Breastfeeding
  • Elderly
  • Increased absorption of liquid paraffin
  • Increased absorption of other fat soluble substances
  • Low-birth-weight infant fatalities

Special populations

Pregnancy

  • Caution 
  • No data available. Use of alternative agents recommended

Breastfeeding

Renal Impairment

Hepatic Impairment

Elderly

Adverse reactions

Immune, Blood and Lymphatic System Disorders

  • Hypersensitivity reactions
  • Anaphylaxis

Interactions

No information available

Mechanism of action

Polysorbates are hydrophilic and are used as emulsifying agents for the preparation of stable oil-in- water emulsions in pharmaceutical products. Polysorbates may also be used for their surfactant properties in preparations for removal of ear wax, and for the management of dry eyes and upper respiratory tract disorders.

Dosage forms

  • Other

References

1. Pharmacologist: Dr Ahmed Abulfathi [https://drive.google.com/file/d/0B-42-QuIVuRHOHdWNHVRR0Fka0FPakRNMTdiRmlWOUJBelZJ/view] 1.1 Martindale Medicines Complete 1.2 https://pubchem.ncbi.nlm.nih.gov/compound/24832082#section=Synonyms 1.3 https://www.medicinescomplete.com/mc/martindale/current/ms-13603-l.htm#r477-a1-1-b-1 1.4 Shelley WB, et al. Lancet 1995; 345: 1312–13. 1.5 ten Tije AJ, et al. Clin Pharmacokinet 2003; 42: 665–85.

Medical aid coverage

data not yet integrated
Discovery Health
not yet integrated
  • Comprehensive Series—
  • Executive Plan—
  • KeyCare Series—
  • Priority Series—
  • Saver Series—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

Bonitas Medical Fund
not yet integrated
  • BonClassic—
  • BonComprehensive—
  • BonEssential—
  • BonFit Select—
  • BonSave—
  • BonStart—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

GEMS — Government Employees Medical Scheme
not yet integrated
  • Beryl—
  • Emerald—
  • Onyx—
  • Ruby—
  • Sapphire—
  • Tanzanite One—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

POLMED — Police Medical Aid Scheme
not yet integrated
  • Aquarium Option—
  • Efficiency Option—
  • Marine Option—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

NeoHealth® ID 15458 · updated 7/12/2022