Sucrose/ Phosphoric Acid

Registered South African indications:

• Nausea

Contraindications

• Hypersensitivity to the active ingredient or any of the excipients in this combination product
• Hereditary fructose intolerance

Cautions

• Pregnancy
• Breastfeeding
• Renal impairment
• Hepatic impairment
• Diabetes mellitus

Forms avail. in SA and covered in this monograph: syr

Symptomatic relief of nausea in motion sickness

Sucrose/ Phosphoric acid
3g/25mg (per 5ml)
3.77g/25mg (per 5ml)

• Oral (syr): 15-30ml, repeated every 15 minutes until distress subsides; Max: 5 doses; Max duration: 1 hour

The dosage should not be diluted. No liquids should be taken for at least 15 minutes before or after administration

Symptomatic relief of nausea in morning sickness

Sucrose/ Phosphoric acid
3g/25mg (per 5ml)

• Oral (syr): 15-30ml, 3hrly and on arising

The dosage should not be diluted. No liquids should be taken for at least 15 minutes before or after administration

Paed. forms avail. in SA and covered in this monograph: syr

Symptomatic relief of nausea in motion sickness

Sucrose/ Phosphoric acid
3g/25mg (per 5ml)
3.77g/25mg (per 5ml)

• Younger than 3 years: Not established for use
• Older than 3 years: Oral (syr): 5-10ml, repeated every 15 minutes until distress subsides; Max: 5 doses; Max duration: 1 hour

The dosage should not be diluted. No liquids should be taken for at least 15 minutes before or after administration

Pregnancy

• FDA Pregnancy Category Not Rated (NR)

Breastfeeding

• Caution

Renal Impairment

• Caution; no information available

Hepatic Impairment

• Caution; no information available

Elderly

• No dose adjustment recommended

Drugs in Sport

• Permitted - No warning

No information available

No information available

None routine

Sucrose
Sucrose is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.The exact pharmacological mechanism of action is unknown, but it has been suggested that sucrose induces endogenous opioid release.

Phosphoric acid
Phosphoric acid is a sequestering agent which binds many divalent cations, including the ionic forms of iron, copper, calcium and magnesium.

Sucrose/ Phosphoric Acid is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

COMBINATION PREPARATIONS

Sucrose/ Phosphoric acid

Syrup (per 5ml) 3.77g/25mg

• Emetrol (Pharmacare)

Syrup (per 5ml) 3g/25mg

• Emex (Mirren)