Sulfiram

These indications are based on manufacturer information for both originator and generic products. For product specific indications, please refer to product specific manufacturer information

South African indications:

• Treatment and prophylaxis of scabies

Contraindications

• Hypersensitivity to the active ingredient or any of its excipients

Cautions

• Pregnancy
• Breastfeeding
• Renal impairment
• Hepatic impairment
• Elderly

Forms avail. in SA and covered in this monograph: soa

Infections caused by Sarcoptes scabiei

General dosing range

• Topical (soa): Apply small quantity to whole body while bathing, especially skin folds, dly

Allow skin to air dry or dry with a towel using a blotting action 

See adult dosage

Pregnancy

• Caution; no information available
• Safety and efficacy have not been established in pregnancy

Breastfeeding

• Caution; no information available
• Safety and efficacy have not been established in breastfeeding

Renal Impairment

• Caution; no information available

Hepatic Impairment

• Caution; no information available

Elderly

• Caution; no information available

Porphyria Information

• Not yet classified (NC)

Drugs in Sport

• Permitted - No warnings

Skin and Subcutaneous Tissue Disorders

• Erythematous rash

Alcohol

None routine

Sulfiram soap is a topical preparation which has been shown to be readily insecticidal against the scabies mite, Sarcoptes scabiei.

Spectrum of activity: Sarcoptes scabiei

Sulfiram is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication

Soap 5%

• Tetmosol (AstraZeneca)