neobookRx
DrugsLevel 4 LocalisationS1SPREML

Thimerosal/ Monoethanolamine/ Ethylenediamine/ Sodium Edetate/ Acetone/ Alcohol 95%

Organomercury compoundAntiseptic, Antifungal

Indications

Registered South African indications:

  • Antiseptic prior to surgery
  • Contaminated wounds
  • Athlete's foot

Cautions

Contraindications

  • Hypersensitivity to the active ingredient or any of its excipients
  • Hypersensitivity to thio or mercury radicals

Cautions

  • Pregnancy
  • Breastfeeding
  • Renal impairment
  • Hepatic impairment
  • Elderly

Adult dosage

Forms avail. in SA and covered in this monograph: spo

Antiseptic prior to surgery
Contaminated wounds
Athlete's foot

  • Topical (spo): Apply small quantity to affected area(s), 8-24hrly

Paediatric dosage

No information available

Special populations

Adverse reactions

Skin and Subcutaneous Tissue Disorders

  • Skin irritation

Interactions

  • Strong acids
  • Salts of heavy metals
  • Iodine

Monitoring

None routine

Mechanism of action

Merthiolate is an antiseptic agent. This action is dependent on thimerosal breaking down and releasing ethyl-mercury which is able to penetrate cell membranes and bind to intracellular enzymes, inhibiting them, and causing cell death.

Dosage forms

  • Spray

Formulation

COMBINATION PREPARATIONS

Acetone/ Alcohol 95%/ Monoethanolamine/ Ethylenediamine/ Sodium edetate/ Thimerosal/ Coloured aqueous vehicle to

Tincture spray (per 100ml) 10ml/52.8ml/100mg/20mg/200mg/100mg/100ml

  • Merthiolate (Pharmacare) Discontinued: 01/04/2018

References

1. SAMF_12th Edition_Page 205 2. https://drive.google.com/drive/folders/1UpSWMYjBf0iB2siXcZ-eK4u4gaHRivW5 (26/09/1974_Pharmacare_Merthiolate_tincture) *no drugs.com *no uptodate *no spc

Brands & products

2 products · cached snapshot
Trade names (1)
  • Merthiolate

SPRSpray · 2 products

from R127.24
ProductStrengthPackApplicantMin price
Merthiolate Spray100 mg/100ml;mg/100ml;mg/100ml;mg/100ml;ml/100ml;ml/100ml30Pharmacare Limited, WoodmeadR127.24
Merthiolatediscontinued100 mg/100ml;mg/100ml;mg/100ml;mg/100ml;ml/100ml;ml/100ml2500Pharmacare Limited, WoodmeadR836.21

Medical aid coverage

data not yet integrated
Discovery Health
not yet integrated
  • Comprehensive Series—
  • Executive Plan—
  • KeyCare Series—
  • Priority Series—
  • Saver Series—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

Bonitas Medical Fund
not yet integrated
  • BonClassic—
  • BonComprehensive—
  • BonEssential—
  • BonFit Select—
  • BonSave—
  • BonStart—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

GEMS — Government Employees Medical Scheme
not yet integrated
  • Beryl—
  • Emerald—
  • Onyx—
  • Ruby—
  • Sapphire—
  • Tanzanite One—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

POLMED — Police Medical Aid Scheme
not yet integrated
  • Aquarium Option—
  • Efficiency Option—
  • Marine Option—

Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.

NeoHealth® ID 14727 · updated 11/30/2022