Thimerosal/ Monoethanolamine/ Ethylenediamine/ Sodium Edetate/ Acetone/ Alcohol 95%
Indications
Registered South African indications:
- Antiseptic prior to surgery
- Contaminated wounds
- Athlete's foot
Cautions
Contraindications
- Hypersensitivity to the active ingredient or any of its excipients
- Hypersensitivity to thio or mercury radicals
Cautions
- Pregnancy
- Breastfeeding
- Renal impairment
- Hepatic impairment
- Elderly
Adult dosage
Forms avail. in SA and covered in this monograph: spo
Antiseptic prior to surgery
Contaminated wounds
Athlete's foot
- Topical (spo): Apply small quantity to affected area(s), 8-24hrly
Paediatric dosage
No information available
Special populations
Pregnancy
Breastfeeding
Renal Impairment
Hepatic Impairment
Elderly
Drugs in Sport
- Permitted - No warning
Adverse reactions
Skin and Subcutaneous Tissue Disorders
- Skin irritation
Interactions
- Strong acids
- Salts of heavy metals
- Iodine
Monitoring
None routine
Mechanism of action
Merthiolate is an antiseptic agent. This action is dependent on thimerosal breaking down and releasing ethyl-mercury which is able to penetrate cell membranes and bind to intracellular enzymes, inhibiting them, and causing cell death.
Dosage forms
- Spray
Formulation
COMBINATION PREPARATIONS
Acetone/ Alcohol 95%/ Monoethanolamine/ Ethylenediamine/ Sodium edetate/ Thimerosal/ Coloured aqueous vehicle to
Tincture spray (per 100ml) 10ml/52.8ml/100mg/20mg/200mg/100mg/100ml
- Merthiolate (Pharmacare) Discontinued: 01/04/2018
References
1. SAMF_12th Edition_Page 205 2. https://drive.google.com/drive/folders/1UpSWMYjBf0iB2siXcZ-eK4u4gaHRivW5 (26/09/1974_Pharmacare_Merthiolate_tincture) *no drugs.com *no uptodate *no spc
Brands & products
2 products · cached snapshot- Merthiolate
SPRSpray · 2 products
from R127.24| Product | Strength | Pack | Applicant | Min price |
|---|---|---|---|---|
| Merthiolate Spray | 100 mg/100ml;mg/100ml;mg/100ml;mg/100ml;ml/100ml;ml/100ml | 30 | Pharmacare Limited, Woodmead | R127.24 |
| Merthiolatediscontinued | 100 mg/100ml;mg/100ml;mg/100ml;mg/100ml;ml/100ml;ml/100ml | 2500 | Pharmacare Limited, Woodmead | R836.21 |
Medical aid coverage
data not yet integrated- Comprehensive Series—
- Executive Plan—
- KeyCare Series—
- Priority Series—
- Saver Series—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- BonClassic—
- BonComprehensive—
- BonEssential—
- BonFit Select—
- BonSave—
- BonStart—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Beryl—
- Emerald—
- Onyx—
- Ruby—
- Sapphire—
- Tanzanite One—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Aquarium Option—
- Efficiency Option—
- Marine Option—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.