Zinc/ Bismuth Subgallate/ Bismuth Oxide

Registered South African indications:

• Haemorrhoids

Contraindications

• Hypersensitivity to the active ingredients or any of the excipients in this combination product

Cautions

• Pregnancy
• Breastfeeding
• Renal impairment
• Hepatic impairment
• Rectal bleeding
• Blood in the stool

Forms avail. in SA and covered in this monograph: sup 

Haemorrhoids
Other related anorectal conditions 

Zinc/ Bismuth Subgallate/ Bismuth oxide
296/59/24 (mg)

• Rectal (sup): 1 sup, in the morning, at bedtime and after every evacuation

Insert as deeply into the anus as possible

Not recommended for use in children

Pregnancy

• Caution
• Whilst formal studies on the effect of this product during human pregnancy have not been conducted, there is no epidemiological evidence of adverse effect, either to the pregnant mother or foetus
• This product should not be used during pregnancy unless the potential benefit of treatment to the mother outweighs the possible risk to the developing foetus

Breastfeeding

• Caution; not recommended
• This product should not be used during breastfeeding unless the potential benefit of treatment to the mother outweighs the possible risk to the breastfeeding infant

Renal Impairment

• Caution; no information available

Hepatic Impairment

• Caution; no information available

Elderly

• No dose adjustment recommended

Porphyria Information

• Not yet classified (NC)

Drugs in Sport

• Permitted - No warnings

Skin and Subcutaneous Tissue Disorders

• Application site reactions
  - Burn
  - Erythema
  - Exfoliation
  - Irritation
  - Pain
  - Pruritus
  - Rash
  - Urticaria

Immune, Blood and Lymphatic System Disorders

• Hypersensitivity

None known

None routine

Persistence or worsening of symptoms

• If symptoms persist or worsen, patients should be instructed to stop use and consult a doctor

Zinc, bismuth subgallate and bismuth oxide provide antiseptic, astringent and emollient properties which help to relieve discomfort associated with minor ano-rectal conditions. This results in a protective action on mucous membranes and raw surfaces.

Zinc/Bismuth Subgallate/Bismuth oxide is available in several formulations. Please note the list below gives examples of products which are available and is not necessarily comprehensive. The listing of a product does not constitute endorsement of the product by EMGuidance; likewise, failure to list a product does not imply that EMGuidance disapproves of the product. This information is put together on the basis of the National Government's Medicines Price Registry at the time of publication.

COMBINATION PREPARATIONS

Zinc/ Bismuth subgallate/ Bismuth oxide

Suppository 296mg/59mg/24mg

• Anusol (Johnson & Johnson) originator