Zinc Sulphate (nasal)
Cautions
Contraindications
- Hypersensitivity to the active ingredient or any of its excipients
- Copper deficiency
Cautions
- Pregnancy
- Breastfeeding
- Renal impairment
- Hepatic impairment
Special populations
Pregnancy
- Caution
- A number of studies did not show foetal abnormalities in pregnant women on oral zinc sulphate 25mg (given in addition to iron and folate). Based on these data, we do not anticipate foetal risk with short term nasal spray of zinc sulphate
Breastfeeding
- Caution
- Inadequate data to determine infant risk. There have been reports of copper deficiency in breastfed infants of mothers on oral zinc acetate
- Short-term use as nasal spray may pose lower risk to infant
Renal Impairment
Hepatic Impairment
Elderly
Porphyria Information
Adverse reactions
Gastrointestinal Disorders
- Dry mouth
- Dry throat
Sensory Disorders
- Local irritant effect
- Discomfort or redness in the eye
- Stinging sensation
Interactions
No information available
Mechanism of action
As a nasal spray, the astringent property of zinc sulphate makes it suitable to be used in the treatment of common cold.
Dosage forms
- Other
References
1. Pharmacologist: Dr Ahmed Abulfathi [https://drive.google.com/file/d/0B4_v8Xoq_6PoOGJYVjhlVzVZNkZiZTJjc2d3WFM3Mnpyb2pj/view] 1.1 Martindale: the complete drug reference 36th edition 1.2 Belongia EA, et al. A randomised trial of zinc nasal spray for the treatment of upper respiratory illness in adults. AM J Med 2001; 111: 103-8 1.3 Merialdi M, et al. Randomised controlled trial of prenatal zinc supplementation and fetal bone growth. Am J Clin Nutr 2004; 79: 826-30 1.4 Product information: GALZIN(R) oral capsules, zinc acetate oral capsules. Teva Pharmaceuticals USA Inc (per DailyMed), North Wales, PA, 2016 1.5 Micromedex solutions 2. U2D: Zinc sulfate: Drug information; Uptodate; Downloaded online; 7 Nov 2018 https://www.uptodate.com/contents/zinc-sulfate-drug-information?search=zinc%20sulfate&source=panel_search_result&selectedTitle=1~28&usage_type=panel&kp_tab=drug_general&display_rank=1 3. NAPOS The Drug Database for Acute Porphyria: Zinc sulphate; Accessed online 07 Nov 2018 http://www.drugs-porphyria.org/languages/UnitedKingdom/s3.php?atc_code=S01AX03&l=gbr 4. South African Institute for Drug-Free Sport: Zinc sulphate; Accessed online 07 Nov 2018 [http://www.drugfreesport.org.za/online-medication-check/]
Medical aid coverage
data not yet integrated- Comprehensive Series—
- Executive Plan—
- KeyCare Series—
- Priority Series—
- Saver Series—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- BonClassic—
- BonComprehensive—
- BonEssential—
- BonFit Select—
- BonSave—
- BonStart—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Beryl—
- Emerald—
- Onyx—
- Ruby—
- Sapphire—
- Tanzanite One—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.
- Aquarium Option—
- Efficiency Option—
- Marine Option—
Formulary scraper pending — coverage tier, co-pay and authorisation requirements will appear here once data is ingested.