Neobook — clinical reference

The publication of this edition of the Primary Healthcare (PHC) Standard Treatment Guidelines (STGs) and Essential Medicines List (EML) is testament of the enthusiasm, dedication, technical expertise and time given by the National Department of Health Essential Drugs Programme, the combined PHC/Adult Hospital Level Expert Review Committee and the National Essential Medicines List Committee (NEMLC). For continuum of care, the PHC STGs have been aligned with the approved NEMLC recommendations contained in the Adult Hospital Level (2024 edition), Paediatric Hospital Level (2023 edition) STGs and EML, in collaboration with the National Department of Health Programmatic Guidelines. The quality of this edition was further enhanced by the constructive collaboration with various stakeholders through the public comment stages of the 2020-2024 STG and EML review cycle.

NATIONAL ESSENTIAL MEDICINES LIST COMMITTEE (2017-2021)
NEMLC members in office during the 2020-2024 review cycle of the combined PHC/AHL STGs and EML are listed below:

Prof A Parrish (Chairperson)
Mrs N Makalima
Prof G Reubenson (Vice-Chairperson)
Dr M Makua
Prof L Bamford
Ms E Maramba
Dr A Black
Ms T Matsitse
Prof S Boschmans
Ms N Mazibuko
Dr RC Chundu
Prof M Mendelson
Prof K Cohen
Ms N Mokoape
Dr R de Waal
Dr N Mpanza
Dr H Dawood
Dr C Mugero
Dr M Dheda
Dr E Mulutsi
Dr N Dlamini
Dr L Mvusi
Ms D du Plessis
Dr R Naidoo
Ms S Dube
Prof N Ndjeka
Prof M Freeman
Dr N Ndwamato
Ms S Govender
Dr L Padayachee
Dr A Gray
Dr Z Pinini
Dr G Grobler
Mr W Ramkrishna
Ms N Gumede
Ms R Reddy
Prof B Hoek
Prof G Richards
Ms K Jamaloodien
Dr A Robinson
Ms Y Johnson
Ms Z Rhemtula
Prof T Kredo
Prof P Ruff
Ms T Links
Mr G Steel
Ms F Loonat
Prof M Tshifularo
Dr J Lotter
Mr G Tshitaudzi
Prof G Maartens
Dr K Vilakazi-Nhlapo
Mr K Mahlako
Mr R Wiseman

NATIONAL ESSENTIAL MEDICINES LIST COMMITTEE (2021- 2024)
NEMLC members in office during the 2020-2024 review cycle of the combined PHC/AHL STGs and EML are listed below:

Dr R de Waal (Co-Chairperson)
Mrs B Molongoana
Prof A Parrish (Co-Chairperson)
Dr K Motse
Ms A Arries-Jacobs
Dr L Mvusi
Prof L Bamford
Ms N Naicker
Prof M Blockman
Dr R Naidoo
Ms F Bongweni
Prof N Ndjeka
Prof K Cohen
Mrs T Njapha
Dr H Dawood
Prof E Osuch
Dr M Dheda
Dr Z Pinini
Ms S Durao
Prof G Reubenson
Ms T Furumele
Ms Z Rhemtula
Dr A Gray
Prof L Robertson
Ms K Jamaloodien
Dr R Romero
Mrs Y Johnson
Prof P Ruff
Prof T Kredo
Dr G Seaketso
Ms B Maclou
Dr B Semete-Makokotlela
Mr K Mahlako
Mr I Setlhare
Mrs L Mahlangu
Ms G Shabangu
Dr K Makgamathe
Ms S Singh
Dr M Makua
Dr K Vilakazi-Nhlapo
Dr H Mamorobela
Mr R Wiseman
Ms E Maramba
Ms P Masilela
Dr M Matandela
Prof M Matlala
Prof M McCaul
Prof J Miot

COMBINED PRIMARY HEALTHCARE/ADULT HOSPITAL LEVEL EXPERT REVIEW COMMITTEE (ERC) AND CO-OPTED MEMBERS (2020-2024)
The ERC members and co-opted members in office during the 2020-2024 review cycle of the combined PHC/AHL STGs and EML are listed below:

Prof K Cohen (Chairperson)
Dr H Dawood (Vice-Chairperson until September 2023)
Prof L Robertson (Vice-Chairperson from October 2023)
Dr K Balme
Ms S Oliviera
Prof M Blockman
Dr M Ramavhuya
Prof H Brits
Dr T Ruder
Prof S Gebhardt
Prof D Gopalan
Prof W Spearman
Dr S Takuva
Prof C Hendrikse
Dr L Jamieson
Dr R Krause
Prof M Levin
Dr G Tatz
Dr J Taylor
Dr G Thom
Prof N Tsabedze
Prof M McCaul
Dr D Van Jaarsveld
Ms S McGee
Dr F Moti
Dr R Mpofu
Prof L Visser
Prof G Watermeyer
Prof M Williams
Dr J Nel
Dr T Zulu
Prof P Nyasulu

HAEMOPHILIA SUBCOMMITTEE (2022-2024)

Dr A Gray (Chairperson)
Prof P Ruff (Vice-Chairperson)
Prof M Blockman
Prof P Jeena
Ms N Makalima
Prof G Reubenson
Dr G Tatz
Mr R Wiseman

EPILEPSY SUBCOMMITTEE (2024-2025)

Prof L Robertson (Chairperson)
Dr A Gray (Vice-Chairperson)
Prof K Cohen
Prof G Reubenson
Prof T Crowley
Dr AC Rossouw
Dr MV Gule
Dr T Ruder
Ms S McGee
Dr J Taylor
Dr U Mehta
Prof J Wilmshurst
Dr KJ Mohale

MEDICINE REVIEW AUTHORS/PEER REVIEWERS and COSTINGS/ ECONOMIC ANALYSES

Ms Z Adam
Ms S McGee
Olawale Ajose
Prof J Miot
Dr Y Balakrishna
Ms B Molongoana
Prof L Bamford
Dr E Mondleki
Dr F Bango
Dr M Moorhouse
Dr E Bera
Dr F Moti
Prof M Blockman
Dr R Mpofu
Ms N Blose
Dr M Mthethwa
Prof H Brits
Dr L Mvusi
Ms M Christofield
Tendai Mvuvu
Prof K Cohen
Mr N Nabyoma
Ms S Dadan
Prof N Ndjeka
Dr N Davies
Dr J Nel
Dr H Dawood
Ms V Ngah
Dr R de Waal
Wandile Ntshangase
Naoko Doi
Ms J Oliver
Dr S Ebrahim
Dr R Osih
Prof L Fairlie
Dr V Pillay-Fuentes Lorente
Ms D Frank
Dr M Reddy
Prof S Gebhardt
Dr R Reddy
Dr N Gloeck
Prof G Reubenson
Prof D Gopalan
Dr J Riddin
Dr A Gray
Prof L Robertson
R Griesel
Prof P Ruff
Dr H Gunter
Sibusiso Simelane
Prof C Hendrikse
Ms H Subedar
Mr A Hohlfeld
Dr S Takuva
Dr L Jamieson
Dr G Tatz
Prof P Jeena
Dr J Taylor
Dr L Johnson
Prof H Temmingh
Dr Idriss Kallon
Dr G Thom
Prof R Krause
Prof N Tsabedze
Prof T Kredo
Dr D van Jaarsveld
Sam Lee
Dr R van Rensburg
Ms T Leong
Dr S van Wyk
Prof G Maartens
Maiyuran Vethakuddikurukka
Ms K MacQuilkan
Prof L Visser
Ms N Makalima
Mrs M Wilkinson
Phatheka Mathola
Mr R Wiseman
Dr H May
Gunter Nicole Young
Prof M McCaul
Ms T Zulu

COMMENTS AND CONTRIBUTIONS

Ms I Ally
Ms N Fakir
Dr K Louw
Dr S Abizu
Dr R Freercks
Prof Q Louw
Ms F Abrahams
Prof L Geerts
Dr L Lumu
Dr B Adam
Dr A Graham
Prof G Maartens
Dr K Alberto
Prof D Gray
Dr S Maasdorp
Dr H Alli
Prof D Hagemeister
Ms C Mabena
Dr M Ariefdien
Prof D Hall
Dr S Maharaj
Ms L Baker
Prof T Hardcastle
Prof J Mahlangu
Dr S Bechan
Ms Melanie Harding (Skeen)
Dr N Maitisa
Ms S Beecum
Dr B Harley
Prof A Makgotloe
Maryke Bezuidenhout
Ms H Hayes
Prof P Makunyane
Dr U Bheku
Ms M Hedder
Prof R Masekela
Dr A Brink
Ms J Herbert
Dr N Mathe
Dr J Burke
Dr M Heredien
Dr N Mayet
Prof R Burnett
Ms L Hiemstra
Dr R Meel Vuka Butelezi
Dr J Hitzeroth
Prof G Meintjies
Dr C Cardona
Dr R Hollhumer
Prof M Mendelson
Dr M Charimbura
Dr S Honikman
Dr F Mitha
Dr K Chetty
Dr T Isaacs
Mr W Modiba
Prof S Chetty
Dr Z Jama
Dr J Mohale
Dr Y Chothia
Prof E Jones
Dr F Mohamed
Dr A Coetzee
Ms J Jones
Dr A Moodley
Ms K Colli-Abrahams
Dr J Joubert
Prof Y Moosa
Dr T Conradie
Dr T Kerbelker
Dr N Moran
Dr K Coutts
Dr S Khan
Prof A Mosam
Dr A Cruickshank
Mr R Kloppers
Ms B Mouton
Dr B Cupido
Prof E Klug
Dr S Munbodh
Prof Z Dangor
Dr J Kluge
Dr L Mvusi
Prof J Dave
Dr D Koot
Mrs V Naicke
Prof R Davids
Ms M Kramer
Dr A Naidoo
Dr B Davidson
Dr S Kraus
Kalpesh Narsi
Dr N Davies
Dr T Kufa-Chakezha
Prof N Ndjeka
Prof P De Witt
Dr C Kyriakakis
Dr J Nuttall
Dr S Dionne
Charlene Lawrence
Dr C Oliphant
Dr K Dladla
Dr R Lehloenya
Prof G Paget
Mr G Doevendans
Dr H LeRiche
Ms L Parkies
Dr J Dreyer
Dr L Levin
Prof F Paruk
Ms D Du Plessis
Ms F Loonat
Dr V Patel
Dr A Pecararo
Ms S Swartz
Leana Persad
Ms Anrie Uys
Dr S Picken
Mr J Van Brakel
Dr V Pillay-Fuentes Lorente
Dr P Van Der Bijl
Dr Pirie
Dr H Van der Merwe
Dr J Potgieter
Dr A Van Rensburg
Prof F Raal
Dr Roland Van Rensburg
Dr M Rabe
Dr Rudi Van Rensburg
Mr W Ramkrishna
Dr M Van Schalkwyk
Prof B Rayner
Dr A van Zyl
Dr K Reddy
Prof A Vanker
Prof P Rheeder
Prof F Venter
Prof A Sarkin
Dr C Verwey
Dr A Scheibe
Prof A von Gottberg
Ms M Schonfeldt
Dr B Vythilingum
Dr H Schutte
Prof N Wearne
Ms V Sekiti
Dr H Weich
Ms G Sibongiseni
Dr J Wessels
Mr N Simo
Dr S Whitelaw
Dr I Singh
Dr S Williams
Prof K Sliwa
Prof J Wilmshurst
Dr M Smith
Dr A Wise
Dr I Sosa Betancourt
Prof DW Wolmarans
Dr D Stead
Prof M Wong
Dr C Stephen
Dr M Zampoli
Dr B Sukha
Prof H Zar
Dr E Swart
Ms T Zulu
Ms A Swart

AbbVie (Pty) Ltd.
AHG Health Services Amgen (Pty) Ltd.
Boehringer Ingelheim Pty Ltd.
Essential Medical Guidance (EMGuidance)
Gates Foundation Johnson & Johnson (Pty) Ltd.
Medicines Information Center - UCT
Medscheme Health Policy Unit
Ministerial Advisory Committee on Antimicrobial Resistance (AMR)
National Advisory Group on Immunisation (NAGI)
National Kidney Foundation of South Africa Organon (Pty) Ltd.
Perinatal Mental Health Project, University of Cape Town
Quantium Health South Africa
Resus Council South Africa
Rural Rehab South Africa (RuReSA)
South African Medicines Formulary (SAMF) Team, UCT.
Society for Endocrinology, Metabolism and Diabetes of South Africa (SEMDSA)
South African Glaucoma
Society South African Haemophilia Foundation (SAHF)
Southern African Spinal Cord Association (SASCA)
The Knowledge Translation Unit, UCT
The Women's Mental Health Special Interest Group within the South African Society of Psychiatrists (SASOP)
Tshwane districts and hospital services
Tygerberg Academic Hospital: Pharmaceutical Services

CLINICAL EDITORIAL REVIEW

Dr R de Waal
Dr R Mpofu

SECRETARIAT

Dr J Jugathpal
Ms M Rapetsoa
Ms Z Adam
Dr M Reddy
Dr R Lancaster
Mrs O Mambinja
Dr J Riddin
Mrs A Brewer
Ms D Frank
Ms K MacQuilkan
Ms N Seedat
Ms TD Leong

LOGISTICS

Mr M Molewa
Ms P Ngobese

CHIEF DIRECTOR: Health Products Procurement

Ms K Jamaloodien

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare Level, 2024 Edition