Brucellosis
Description Medicine Treatment ICD-10 code: A23.0-3/A23.8-9 *Notifiable medical condition. DESCRIPTION Zoonotic infection, usually due to B. abortus in South Africa. Infection is usually acquired from unpasteurised milk products or handling raw meat. MEDICINE TREATMENT Doxycycline, oral, 100 mg 12 hourly for 6 weeks. AND Gentamicin, IV, 6 mg/kg daily for 3 weeks (see Appendix II for guidan
ICD-10 code: A23.0-3/A23.8-9
*Notifiable medical condition.
DESCRIPTION
Zoonotic infection, usually due to B. abortus in South Africa. Infection is usually acquired from unpasteurised milk products or handling raw meat.
MEDICINE TREATMENT
- Doxycycline, oral, 100 mg 12 hourly for 6 weeks.
AND
- Gentamicin, IV, 6 mg/kg daily for 3 weeks (see Appendix II for guidance on prescribing).
- Preferred regimen for osteo-articular or cardiac involvement.
LoE:IVbxxiii
Alternatively, REPLACE gentamicin with rifampicin:
- Rifampicin, oral, 7.5 mg/kg 12 hourly for 6 weeks.
Exclude TB before starting rifampicin-based therapy.
Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.2_20 January 2025
Chapter 9 Systemic and Healthcare-Associated Infections_9.3 Brucellosis