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Cerebral Abscess

Infection Cerebral abscess Brief outline/clinical setting May be as a result of contiguous spread of organisms, haematogenous spread, or iatrogenic Discuss with Neurology/Neurosurgery for aspiration and culture Aetiologies/organisms S.aureus, S.anginosus group, Enterobacterales, other Streptococci, anaerobes, Nocardia spp. Optimal antimicrobial selection 3rd gen cephalosporin (cefotaxime 8-12 g/d

Infection Cerebral abscess
Brief outline/clinical setting May be as a result of contiguous spread of organisms, haematogenous spread, or iatrogenic
Discuss with Neurology/Neurosurgery for aspiration and culture
Aetiologies/organisms S.aureus, S.anginosus group, Enterobacterales, other Streptococci, anaerobes, Nocardia spp.
Optimal antimicrobial selection 3rd gen cephalosporin (cefotaxime 8-12 g/day or ceftriaxone 4 g/day) + metronidazole (1.5 g/day)
Duration Total of 6 weeks of therapy. Tailor antimicrobial therapy once culture and antimicrobial susceptibility results are available
Alternative if allergic/not available Discuss with Infectious Diseases/ Microbiology
Rationale  
Level of evidence High
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Drugs mentioned

NeoHealth® ID 23834 · updated 3/26/2024