GuidelinesOther guideline
Cerebral Abscess
Infection Cerebral abscess Brief outline/clinical setting May be as a result of contiguous spread of organisms, haematogenous spread, or iatrogenic Discuss with Neurology/Neurosurgery for aspiration and culture Aetiologies/organisms S.aureus, S.anginosus group, Enterobacterales, other Streptococci, anaerobes, Nocardia spp. Optimal antimicrobial selection 3rd gen cephalosporin (cefotaxime 8-12 g/d
| Infection | Cerebral abscess |
| Brief outline/clinical setting | May be as a result of contiguous spread of organisms, haematogenous spread, or iatrogenic Discuss with Neurology/Neurosurgery for aspiration and culture |
| Aetiologies/organisms | S.aureus, S.anginosus group, Enterobacterales, other Streptococci, anaerobes, Nocardia spp. |
| Optimal antimicrobial selection | 3rd gen cephalosporin (cefotaxime 8-12 g/day or ceftriaxone 4 g/day) + metronidazole (1.5 g/day) |
| Duration | Total of 6 weeks of therapy. Tailor antimicrobial therapy once culture and antimicrobial susceptibility results are available |
| Alternative if allergic/not available | Discuss with Infectious Diseases/ Microbiology |
| Rationale | |
| Level of evidence | High |
| Link to Guideline | Click here |