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Cholecystitis, Acute and Cholangitis, Acute

General measures Medicine treatment Referral ICD-10 code : K81.0/K83.0 GENERAL MEASURES  Surgical drainage/cholecystectomy according to indication and/or patient's condition. MEDICINE TREATMENT Acute cholecystitis Mild and asymptomatic cases without risk factors may not require antibiotic treatment. If signs of infection present and/or risk factors for severe disease are present, such a

General measures

Medicine treatment

Referral


ICD-10 code: K81.0/K83.0

GENERAL MEASURES 

Surgical drainage/cholecystectomy according to indication and/or patient's condition.

MEDICINE TREATMENT

Acute cholecystitis

Mild and asymptomatic cases without risk factors may not require antibiotic treatment. If signs of infection present and/or risk factors for severe disease are present, such as:

  • Elderly patients (>60 years of age)
  • Co-morbid conditions
  • Immune compromised

Acute cholecystitis and acute cholangitis

  • Amoxicillin/clavulanic acid, oral, 875/125 mg 12 hourly.

If unable to tolerate oral therapy:

  • Amoxicillin/clavulanic acid, IV, 1.2 g 8 hourly.

REFERRAL 

  • Clinical deterioration or failure to improve.
  • Fistulae or perforation.
  • Need for complicated surgery

Click here for the pdf. 


Standard Treatment Guidelines And Essential Medicines List For South Africa, Adult Hospital level, 2020-4_Version 1_July 2024

Chapter 1: Alimentary tract; 1.2 Hepatic Disorders; 1.2.7 Cholecystitis, Acute and Cholangitis, Acute

Drugs mentioned

ICD-10 codes

NeoHealth® ID 17768 · updated 2/10/2025