Coagulation Factors
Description Medicine Treatment Description Cryoprecipitate Cryoprecipitate is a source of fibrinogen, factor VIII, factor XIII, and von Willebrand factor. Active bleeding with a low fibrinogen level (<2g/L) is the main indication for cryoprecipitate in critical care and is common in obstetric haemorrhage and trauma. Cryoprecipitate administration may also be guided by viscoelastic testing in m
Description
Cryoprecipitate
- Cryoprecipitate is a source of fibrinogen, factor VIII, factor XIII, and von Willebrand factor.
- Active bleeding with a low fibrinogen level (<2g/L) is the main indication for cryoprecipitate in critical care and is common in obstetric haemorrhage and trauma.
- Cryoprecipitate administration may also be guided by viscoelastic testing in major haemorrhage.
Medicine Treatment
- Cryoprecipitate, IV, 1 unit per 10 kg total body weight (South African National Blood Services), or 1 pooled unit (Western Cape Blood Services)
Vitamin K-dependent clotting factors:
For warfarin poisoning, see: Anticoagulant (Warfarin and Rodenticide Superwarfarin) Poisoning.
For other coagulation factor-related disorders, see Blood And Blood Forming Organs.
Standard Treatment Guidelines and Essential Medicines List for South Africa Adult Hospital _Chapter 23: Adult Critical Care_NEMLC Medicine Recommendations Review Cycle_ 2020_2023