GuidelinesOther guideline
Complicated UTI
Infection Complicated UTI Brief outline/clinical setting defined as symptomatic cystitis in men, patients with structural abnormalities of the urinary tract (UT) or indwelling catheters and pregnant women, or conditions leading to an immunocompromised state, e.g. HIV, diabetes. Important to submit urine for MC&S prior to starting therapy Aetiologies/organisms Enterobacterales: E. coli, K. pne
| Infection | Complicated UTI |
|---|---|
| Brief outline/clinical setting |
defined as symptomatic cystitis in men, patients with structural abnormalities of the urinary tract (UT) or indwelling catheters and pregnant women, or conditions leading to an immunocompromised state, e.g. HIV, diabetes. |
| Aetiologies/organisms | Enterobacterales: E. coli, K. pneumoniae, Enterobacter spp, Proteus spp S. saprophyticus, Group B streptococcus, Enterococcus spp. |
| Optimal antimicrobial selection | Amoxicillin/clavulanate plus an aminoglycoside (recommendation grade: strong) A second generation cephalosporin plus an aminoglycoside (recommendation grade: strong) A third generation cephalosporin intravenously as empirical treatment of complicated UTI with systemic symptoms (recommendation grade: strong) |
| Duration | Dependent on agent used, and response to therapy |
| Alternative if allergic/not available | See above |
| Rationale | |
| Level of evidence |