neobookRx
GuidelinesIMCI

Cotrimoxazole (Age 2 months up to 5 years)

IMCI - Child (Age 2 months up to 5 years)

Give Cotrimoxazole Once Daily as Prophylaxis

  • Give to all children with HIV infection (criteria for stopping in children on ART are shown below)
Indications
When to start
When to stop
HIV-infected infants (< 1 year of age)
From 6 weeks of age
Continue until 1 year of age, regardless of clinical stage and CD4 count
HIV-positive children 1-5 years of age.
All symptomatic children: WHO clinical stage 2, 3 or 4
OR
CD4 <25% / CD4 <500 cells/ μl.
Stop if clinically well on ART and CD4 ≥25% or ≥500 cells/μl on ≥2 occasions 3-6 months apart
Recommence if CD4 drops <200 cells/μl, if ART fails or if new opportunistic infection develops
HIV-positive children ≥ 5 years of age, adolescents and adults.
Start if CD4 <200 cell/μl
OR
Clinical stage 3 or 4 disease (including TB)
Stop if clinically well on ART and CD4 ≥200 cells/μl on ≥2 occasions 3-6 months apart. Recommence if CD4 drops below 200 cells/ μl

 

Weight
Cotrimoxazole syrup 
(200/40 mg per 5 ml)
Cotrimoxazole tablet 
400/80 mg
Cotrimoxazole tablet 
800/160 mg
2.5 - < 5 kg
2.5 ml
1/4 tablet
 
5 - < 14 kg
5 ml
1/2 tablet
 
14 - < 30 kg
10 ml
1 tablet
1/2 tablet
≥ 30 kg
 
2 tablets
1 tablet


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Integrated Management of Childhood Illness 2022; Child (Age 2 months up to 5 years); Oral Medicines; Cotrimoxazole


Last checked for updates: June 2023 

NeoHealth® ID 18288 · updated 8/18/2023