Cotrimoxazole Poisoning
Description General measures T37.0 + (X44.99/X64.99/Y14.99) DESCRIPTION Acute overdose is associated with a low probability of clinically relevant toxicity. Symptoms include nausea and vomiting, dizziness, headache, and neurological symptoms (such as drowsiness, confusion, and mental depression). Other signs include bone marrow depression, haematuria, and renal insufficiency. Hypersensitivity rea
T37.0 + (X44.99/X64.99/Y14.99)
DESCRIPTION
Acute overdose is associated with a low probability of clinically relevant toxicity. Symptoms include nausea and vomiting, dizziness, headache, and neurological symptoms (such as drowsiness, confusion, and mental depression). Other signs include bone marrow depression, haematuria, and renal insufficiency. Hypersensitivity reactions may occur.
GENERAL MEASURES
- Treatment is symptomatic and supportive.
- Monitor FBC, electrolytes, glucose, hepatic and renal function in symptomatic patients.
Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 2.0_27 March 2025
Chapter 19 Poisoning_19.12 Cotrimoxazole Poisoning
ICD-10 codes
- T37.0Poisoning, sulfonamides
- X44.99Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances, unspecified place, during unspecified activity
- X64.99Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances, unspecified place, during unspecified activity
- Y14.99Poisoning by and exposure to other and unspecified drugs, medicaments and biological substances, undetermined intent, unspecified place, during unspecified activity