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Cyanotic/Acyanotic Cardiac Lesions

Management guidelines for students, interns and registrars on a variety of routine and emergency situations in our neonatal service at Tygerberg Children’s Hospital. Published in 2014.

*The Hypertoxic Test

Prostin E



*The Hypertoxic Test

  • Determine arterial blood gas in room air
  • Administer 100% O2 for 10 minutes
  • Repeat blood gas. If PaO2 <150 mmHg (±20 kPa) one can assume central mixing is occuring

In the majority of cyanotic heart lesions the PaO2 should not exceed 10 kPa

Prostin E

A 1/4 tablet is given initially every hour p.o to keep the ductus open in all suspected congenital cyanotic heart lesions.



NeoHealth® ID 20041 · updated 9/15/2021