Erythema Multiforme

Description

Referral

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L51.0/L51.8-9

DESCRIPTION

• A self-limiting and commonly recurrent inflammatory eruption of the skin
• May involve mucous membrane (but not more than one surface), and usually without systemic symptoms
• Usually lasts for 10–14 days before complete recovery occurs
• Symmetrically distributed crops of target lesions (dark centre, an inner, pale ring surrounded by an outer red ring) occur on the extremities, and in particular, on the backs of the hands and forearms, palms and soles
• This condition is usually due to an infection, commonly herpes simplex or mycoplasma

REFERRAL

• All patients with systemic symptoms or mucosal involvement
• Unsure of the diagnosis

Click here to access the pdf.

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-2024_Review-Version-2.0-November-2025

Chapter 5: Skin Conditions_5.10.5 Erythema Multiforme