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Fixed Drug Eruptions

Allergies

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Click here to access the Primary-Healthcare-Chapter-5-Skin-Conditions-with-Supporting-NEMLC-Report-2020-4-Review-Version-2.0-November-2025


Description

General Measures

Medicine Treatment

Referral


ICD 10 code: L27.0-1

DESCRIPTION

  • Dark coloured round macules that can occur anywhere on the body following the ingestion of a medicine to which the patient has become allergic
  • They recur on the same spot and increase in number with each successive attack
  • In the acute stage they are itchy, red around the edge or even bullous

GENERAL MEASURES (ALL PATIENTS)

  • Stop the offending medicine(s)

MEDICINE TREATMENT (ALL PATIENTS)

Acute/active stage

  • Hydrocortisone 1%, topical, apply daily for 5 days

LoE: IVb

REFERRAL

  • Widespread eruptions

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-2024_Version 1.0_07 November 2024

Chapter 5: Skin Conditions_5.10.3. Fixed Drug Eruptions

Drugs mentioned

ICD-10 codes

NeoHealth® ID 17197 · updated 4/28/2026