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Herpes Keratitis and Conjunctivitis

Description Diagnostic criteria General and supportive measures Medicine treatment Referral ICD-10 code: B00.5 DESCRIPTION Herpes infection of the cornea and/or conjunctiva. DIAGNOSTIC CRITERIA There are three most common forms of this disease. Blepharoconjunctivitis Primary ocular infection involving the eyelids and/or conjunctivae. The condition is benign and self-limiting. May be associated wi

Description

Diagnostic criteria

General and supportive measures

Medicine treatment

Referral


ICD-10 code: B00.5

DESCRIPTION

Herpes infection of the cornea and/or conjunctiva.

DIAGNOSTIC CRITERIA

There are three most common forms of this disease.

Blepharoconjunctivitis

  • Primary ocular infection involving the eyelids and/or conjunctivae.
  • The condition is benign and self-limiting.
  • May be associated with keratitis: tiny punctuate stains on the cornea when stained with fluorescein and viewed with the cobalt blue light of the direct ophthalmoscope.

Disciform keratitis

  • Immune response to herpes virus.
  • Decreased visual acuity and corneal sensation.
  • Round, dull, swollen area in the central cornea.
  • Decreased sensation when compared to the other eye. (Use a thread of cotton from a cotton bud and touch the cornea from the side, away from the visual axis).
  • Refer to an ophthalmologist.

Dendritic ulcer

  • A linear branching ulcer (dendritic ulcer) when stained with fluorescein and viewed with the cobalt blue light of the direct ophthalmoscope.
  • Decreased sensation when compared to the other eye. (Use a thread of cotton from a cotton bud and touch the cornea from the side, away from the visual axis).

GENERAL AND SUPPORTIVE MEASURES

Pad the eye.

MEDICINE TREATMENT

  • Aciclovir, ophthalmic ointment, applied 5 times per day for 10 days.

OR

  • Aciclovir, orally, 20 mg/kg, 5 times per day for 10 days.

If painful ciliary spasm is present:

  • Atropine, ophthalmic drops, instil 1 drop, 12 hourly.

LoE II1, III2

REFERRAL

Urgent within 24 hours:

  • If the corneal lesion is not clean/clear or has whitish areas within the bed of the epithelial ulcer.
  • If the area of corneal staining is not smaller within 24 hours of treatment.
  • If there is a history of recurrence.
  • Disciform keratitis for assessment and treatment.

Click here for the pdf.


Standard Treatment Guidelines and Essential Medicines List for South Africa Paediatric Hospital _2023, 5th edition_Updated July 2024 

Chapter 16: Eye Conditions,  16.3 Herpes Keratitis And Conjunctivitis

Drugs mentioned

ICD-10 codes

NeoHealth® ID 17683 · updated 10/27/2024