Human Bites
Description Medicine Treatment Referral ICD-10 code: S01.0-9/S11.0-2/S11.7-9/S21.0-2/S21.7-9/S31.0-5/S31.7-8/S41.0-1/S41.7-8/S51.0/S51.7-9/S61.0- 1/S61.7-9/S71.0-1/S71.7-8/S81.0/S81.7-9/S91.0-3/S91.7/T01.0-3/T01.6/T01.8- 9/T09.1/T11.1/T13.1/T14.0-1 + External Cause Code (W,X,Y,Z) DESCRIPTION Human bites may be accidental or intentional (form of assault). Human bites may result in:&nb
ICD-10 code: S01.0-9/S11.0-2/S11.7-9/S21.0-2/S21.7-9/S31.0-5/S31.7-8/S41.0-1/S41.7-8/S51.0/S51.7-9/S61.0- 1/S61.7-9/S71.0-1/S71.7-8/S81.0/S81.7-9/S91.0-3/S91.7/T01.0-3/T01.6/T01.8- 9/T09.1/T11.1/T13.1/T14.0-1 + External Cause Code (W,X,Y,Z)
DESCRIPTION
- Human bites may be accidental or intentional (form of assault).
- Human bites may result in:
- Wound infection, often due to mixed aerobic and anaerobic infection.
- Puncture wounds.
- Tissue necrosis.
- Transmission of diseases, e.g. HIV, hepatitis.
MEDICINE TREATMENT
Wound management:
Wash wound thoroughly with soap under running water for 5–10 minutes.
- Chlorhexidine 0.05%, aqueous solution.
Apply disinfectant if available:
- Povidone-iodine 10%, solution.
CAUTION
Do not suture bite wounds unless on the head/face. Clean thoroughly, dress (avoid compressive dressings). Review after 48 hours for secondary closure at that time.
Tetanus prophylaxis:
ICD-10 code: Z23.5
If not previously immunised within the last 5 years:
- Tetanus toxoid (TT), IM, 0.5 mL.
Antibiotic treatment:
Adults and Children > 35 kg
- Amoxicillin/clavulanic acid, oral, 875/125 mg 12 hourly for 5 days.
Children ≤ 35 kg
- Amoxicillin/clavulanic acid oral, 15–25 mg/kg/dose of amoxicillin component, 8 hourly for 5 days.

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Severe penicillin allergy:
ICD-10 code: Z88.0
Adults and Children > 35 kg
- Macrolide, e.g.:
Azithromycin, oral, 500 mg daily for 3 days
Children
- Macrolide, e.g.:
- Azithromycin, oral, 10 mg/kg daily for 3 days. See dosing table.
AND
Adults
- Metronidazole, oral, 400 mg, 8 hourly for 5 days
Children
- Metronidazole, oral, 7.5 mg/kg/dose 8 hourly for 5 days. See dosing table.
Hepatitis B prophylaxis (if bite is severe enough to cause bleeding):
ICD-10 code: Z29.8
See: Post exposure prophylaxis, inadvertent (non-occupational).
HIV prophylaxis
The risk of HIV transmission through biting is negligible. Post-exposure prophylaxis is not indicated after a bite.
REFERRAL
- Deep and large wounds requiring suturing.
- Shock and bleeding.
- Severe infected wounds or infected wounds not responding to oral antibiotics.
- Hand bites.
Click here for the NEMLC Recommendations for medicine amendments (2020-4 review cycle).
Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-4_Version 1.1_October 2024
Chapter 21: Emergencies and Injuries
Drugs mentioned
ICD-10 codes
- S01.0Open wound of scalp
- S01.1Open wound of eyelid and periocular area
- S01.2Open wound of nose
- S01.3Open wound of ear
- S01.4Open wound of cheek and temporomandibular area
- S01.5Open wound of lip and oral cavity
- S01.7Multiple open wounds of head
- S01.8Open wound of other parts of head
- S01.9Open wound of head, part unspecified
- S11.0Open wound involving larynx and trachea
- S11.1Open wound involving thyroid gland
- S11.2Open wound involving pharynx and cervical oesophagus
- S11.7Multiple open wounds of neck
- S11.8Open wound of other parts of neck
- S11.9Open wound of neck, part unspecified
- S21.0Open wound of breast
- S21.1Open wound of front wall of thorax
- S21.2Open wound of back wall of thorax
- S21.7Multiple open wounds of thoracic wall
- S21.8Open wound of other parts of thorax
- S21.9Open wound of thorax, part unspecified
- S31.0Open wound of lower back and pelvis
- S31.1Open wound of abdominal wall
- S31.2Open wound of penis
- S31.3Open wound of scrotum and testes
- S31.4Open wound of vagina and vulva
- S31.5Open wound of other and unspecified external genital organs
- S31.7Multiple open wounds of abdomen, lower back and pelvis
- S31.8Open wound of other and unspecified parts of abdomen
- S41.0Open wound of shoulder
- S41.1Open wound of upper arm
- S41.7Multiple open wounds of shoulder and upper arm
- S41.8Open wound of other and unspecified parts of shoulder girdle
- S51.0Open wound of elbow
- S51.7Multiple open wounds of forearm
- S51.8Open wound of other parts of forearm
- S51.9Open wound of forearm, part unspecified
- S61.0Open wound of finger(s) without damage to nail
- S61.7Multiple open wounds of wrist and hand
- S61.8Open wound of other parts of wrist and hand
- S61.9Open wound of wrist and hand part, part unspecified
- S71.0Open wound of hip
- S71.1Open wound of thigh
- S71.7Multiple open wounds of hip and thigh
- S71.8Open wound of other and unspecified parts of pelvic girdle
- S81.0Open wound of knee
- S81.7Multiple open wounds of lower leg
- S81.8Open wound of other parts of lower leg
- S81.9Open wound of lower leg, part unspecified
- S91.0Open wound of ankle
- S91.1Open wound of toe(s) without damage to nail
- S91.2Open wound of toe(s) with damage to nail
- S91.3Open wound of other parts of foot
- S91.7Multiple open wounds of ankle and foot
- T01.0Open wounds involving head with neck
- T01.1Open wounds involving thorax with abdomen, lower back and pelvis
- T01.2Open wounds involving multiple regions of upper limb(s)
- T01.3Open wounds involving multiple regions of lower limb(s)
- T01.6Open wounds involving multiple regions of upper limb(s) with lower limb(s)
- T01.8Open wounds involving other combinations of body regions
- T09.1Open wound of trunk, level unspecified
- T11.1Open wound of upper limb, level unspecified
- T13.1Open wound of lower limb, level unspecified
- T14.0Superficial injury of unspecified body region
- T14.1Open wound of unspecified body region
- Z23.5Need for immunization against tetanus alone
- Z29.8Other specified prophylactic measures
- Z88.0Personal history of allergy to penicillin