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Impetigo

Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition

Description

General Measures

Medicine Treatment


L01.0-1A + (B95.0-8)

DESCRIPTION

Superficial skin infection, starting as vesicles with an inflammatory halo. Later a characteristic honey-coloured crust on erythematous base develops which heals without scarring. Usually caused by group A streptococci or staphylococci. Post-streptococcal glomerulonephritis is a potential complication.

GENERAL MEASURES

  • Good personal and household hygiene to reduce carriage of organisms and spread of infection.
  • Wash and soak lesions in soapy water to soften and remove crusts.

MEDICINE TREATMENT

Antibiotic therapy

  • Flucloxacillin, oral, 500 mg 6 hourly for 5 days

Severe penicillin allergy: (Z88.0)

  • Macrolide, e.g.:
    • Azithromycin, oral, 500 mg daily for 3 days

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_07 November 2024

Chapter 4 Dermatology_4.3 Impetigo

Drugs mentioned

ICD-10 codes

NeoHealth® ID 17686 · updated 7/8/2025