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Itching (Pruritus)

Itching (Pruritus)

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Click here to access the Primary-Healthcare-Chapter-5-Skin-Conditions-with-Supporting-NEMLC-Report-2020-4-Review-Version-2.0-November-2025


Description

General Measures

Medicine Treatment

Referral


ICD 10 code: L29.0-3/L29.8-9

DESCRIPTION

Itching may be:

  • Localised or generalised
  • Accompanied by obvious skin lesions or skin conditions e.g. chicken pox
  • Accompanied by many systemic diseases, e.g. hepatitis
  • Caused by scabies and insect bites

GENERAL MEASURES

  • Diagnose and treat the underlying condition
  • Trim fingernails
  • Avoid scratching

MEDICINE TREATMENT

  • Calamine lotion, apply when needed

For pruritus associated with dry skin:

  • Emollient, e.g.:
    • Emulsifying ointment (UE)

If pruritis is severe and requires short term control:

Children

  • Chlorphenamine, oral, 0.1 mg/kg/dose 6–8 hourly. See: dosing table

Adults

  • Chlorphenamine, oral, 4 mg, 6–8 hourly

LoE:IVb1


Note:

Chlorphenamine is sedating and may only be required in the evening for mild cases. 


If pruritis is severe and requires long term control, e.g. for chronic pruritus: 

Children: 2–6 years of age

Children > 6 years of age and adults

  • Cetirizine, oral, 10 mg once daily

REFERRAL

  • No improvement after 2 weeks
  • Underlying malignancy or systemic disease suspected

Click here to access the pdf.


Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-2024_Version 1.0_07 November 2024

Chapter 5: Skin Conditions_5.2 Itching (Pruritus)

Drugs mentioned

ICD-10 codes

NeoHealth® ID 19641 · updated 4/24/2026