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Management Of Asphyxia Neonatorum

Management guidelines for students, interns and registrars on a variety of routine and emergency situations in our neonatal service at Tygerberg Children’s Hospital. Published in 2014.

  • Saturation:                                                     
    • Maintain SaO2  92-95% in term baby
    • Maintain SaO2  88-92% in preterm baby
  • Capillary filling time:                          
    • If longer than 3 seconds, consider stabilised human serum or 0.9% physiological NaCl solution (Saline)
  • Blood pressure:                                   
    • Maintain systolic blood pressure at 55-65 mmHg
    • Hypotensive - consider Dopamien 5-20µg/ Kg/min
  • Urine output:                                       
    • Monitor output. If urine <1 ml/Kg/hour over 6 hours, restrict fluid, give Lasix(R) 1-2 mg/ Kg/IV every 6 hrs prn
  • Investigations:                                     
    • Electrolytes, acid-base status, glucose, calcium and magnesium, CK.
    • Cranial ultrasound / EEG as indicated
  • Intravenous fluid:                               
    • Use K+-free fluid e.g. 5-10% D/W in 0.2% NaCl    solution
    • or K+-free Neonatalyte.  Restrict fluid.
  • Convulsions:                                        
    • Phenobarbitone, Epanutin, Lorazepam, etc
  • Metabolic acidosis:                              
    • Correct if necessary
  • Clotting diathesis:                               
    • Manage as indicated
  • Persistent pulmonary hypertension:
    • Oxygenate and correct acidosis

Drugs mentioned

NeoHealth® ID 18233 · updated 9/15/2021