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Massive Transfusion Guidelines: Summary

Massive transfusion

  • Recognise the need for massive transfusion.
  • Declare the situation to the entire team.
  • Notify Anaesthesia and Surgery consultant-on-call.
  • Draw baseline blood specimens:
    • FBC
    • Creatinine, urea, electrolytes
    • INR
    • Cross-match tube (if not sent already)
  • Keep the patient warm.
  • Consider Tranexamic Acid (Cyclokapron) 1g IV over 10 minutes.
  • Check with blood bankthat they have received an adequate cross-match specimen.
  • Request Massive Transfusion Pack:
    • 6 units packed red blood cells.
    • 6 units FFP (fresh frozen plasma).
    • 1 unit of random donor pooled platelets.
  • Put request through as STAT and not ASAP.
  • Ensure adequate large-bore high-capacity venous access.
  • Ensure active warming of patient and IV fluids.
  • Commence transfusion on arrival of products.
  • Repeat “Massive Transfusion Pack” as necessary.
  • Consider the addition of 10 units (1000iu) cryoprecipitate when ordering second and subsequent Massive Transfusion Packs.
  • Before transferring to ICU, contact laboratory and send STAT blood for:
    • FBC (Hb & platelet count)
    • INR & PTT
    • Fibrinogen levels
  • Repeat Tranexamic Acid 1g in 200ml or 1000ml saline over 8 hrs in ICU.

Drugs mentioned

NeoHealth® ID 18803 · updated 9/15/2021