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Otitis Externa (OE)

Infection Otitis externa (OE) Brief outline/clinical setting Acute OE is defined as diffuse inflammation of the ear canal, which may also involve the pinna or tympanic membrane. Acute OE usually occurs rapidly over a 48 hour period. Patients with acute OE present with tenderness and oedema of the tragus, pinna or both, secondary to cellulitis of the ear canal skin and sub-dermis. Patients at risk

Infection Otitis externa (OE)
Brief outline/clinical setting Acute OE is defined as diffuse inflammation of the ear canal, which may also involve the pinna or tympanic membrane.
Acute OE usually occurs rapidly over a 48 hour period.
Patients with acute OE present with tenderness and oedema of the tragus, pinna or both, secondary to cellulitis of the ear canal skin and sub-dermis.
Patients at risk of OE include those with diabetes and immunocompromised patients.
Aetiologies/organisms OE is usually of bacterial aetiology.
Common pathogens:
Pseudomonas aeruginosa
Staphylococcus aureus

Fungi - usually involved in chronic OE or after treatment of acute OE with antibiotics
Optimal antimicrobial selection

Clinicians should prescribe topical therapy initially for diffuse uncomplicated acute OE.

TOPICAL THERAPY FOR DIFFUSE UNCOMPLICATED ACUTE OE:

  1. Acetic acid 2% solution
  2. Acetic acid 2%, hydrocortisone 1.0%
  3. Ciprofloxacin 0.2%, hydrocortisone 1.0%
  4. Ciprofloxacin 0.3%, dexamethasone 0.1%
  5. Neomycin, polymyxin B, hydrocortisone
  6. Ofloxacin 0.3%

NON INTACT TYMPANIC MEMBRANE:

Non-ototoxic topical preparation

INDICATIONS FOR SYSTEMIC ANTIMICROBIALS:

- Extension outside the ear canal
- Host factors e.g. immunocompromised individual, diabetes

SYSTEMIC ANTI MICROBIAL OPTIONS: In consultation with ENT and microbiology
Anti pseudomonal antimicrobial options:

  1. Piperacillin – tazobactam – 4.5gm iv 6 hourly (Will treat Staphylococcus aureus also)
  2. Ceftazidime – 2 gm iv 8 hourly

Antimicrobials to be adjusted based on culture and susceptibility results.

Duration  
Alternative if allergic/not available Discuss with Microbiology/ID
Rationale
 Clinical Practice Guideline: Acute Otitis Externa Executive Summary 2014 (American Academy of Otolaryngology Head and Neck Surgery)

Level of evidence High for efficacy of topical therapy
Link to Guideline  

Drugs mentioned

NeoHealth® ID 23855 · updated 3/27/2024