neobookRx

Otitis Media, Acute

Otitis

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Click here to access the Primary-Healthcare-Chapter-19-Ear-Nose-and-Throat-with-supporting-NEMLC-report-2020-4-review-2-December-2025


Description 

General Measures 

Medicine Treatment 

Referral


ICD-10 Code: H66.9

DESCRIPTION

Inflammation of the middle ear characterised by:

  • Pain
  • Loss of hearing
  • Red bulging eardrum
  • Drum perforation
  • Fever in about half of the cases
  • Loss of the normal light reflex of the eardrums

Mild redness of the eardrum and rubbing the ear are not reliable signs.

GENERAL MEASURES

  • Do not instil anything into the ear
  • Avoid getting the inside of the ear wet
  • Dry mop ear if discharge is present
  • Do not plug the ear with cotton wool, etc
  • Exclude HIV infection as a contributing factor for recurrent ear infection

MEDICINE TREATMENT

Children 

  • Amoxicillin, oral, 45 mg/kg/dose 12 hourly for 5 days.

Weight 
kg

Dose 
mg

Use one of the following:

Age 
Months/ years

Syrup 
mg/ 5 mL

Capsule 
mg

125

250

250

500

>3.5–5 kg

175 mg 

7 mL

3.5 mL

-

-

>1–3 months

>5–7 kg

250 mg

10 mL

5 mL

-

-

>3–6 months

>7–11 kg

375 mg

15 mL

7.5 mL

-

-

>6–18 months

>11–14 kg

500 mg

-

10 mL

2

1

>18 months–3 years

>14–17.5 kg

750 mg

-

15 mL

3

-

>3–5 years

>17.5–25 kg

1000 mg

-

20 mL*

4

2

>5–7 years

>25-30 kg
1250 mg
-
25 mL*
5
-
>7-10 years
>30 kg
1500 mg
-
-
6
3
>10 years
  • Review response after 5 days

LoE:III386

  • If pain or discharge persists, consider alternative diagnosis and continue antibiotics for a further 5 days

LoE:III387

Adults

  • Amoxicillin, oral, 1500 mg 12 hourly for 5 days

LoE:III388

Antibiotic treatment for those who have taken amoxicillin in the previous 30 days; or poor response to 10-day course of amoxicillin: 

Children 

  • Amoxicillin/ clavulanic acid, oral, 15–25 mg/kg/dose of amoxicillin component, 8 hourly for 5-10 days

Weight 
kg

Dose
mg
(amoxicillin component)

Use one of the following:

Age 
months/ years

Susp
125/31.5 mg/5 mL 

Susp
250/62.5 mg/5 mL

Tablet 
500/125 mg/tab

>3.5–5 kg

75 mg

3 mL

1.5 mL

-

>1–3 months

>5–7 kg

100 mg 

4 mL

2 mL

-

>3–6 months

>7–9 kg

150 mg

6 mL

3 mL

-

>6–12 months

>9-11 kg

200 mg 

8 mL

4 mL

-

>12-18 months 

>11-14 kg
250 mg
10 mL
5 mL

-

>18 months-3 years
>14-17.5 kg
300 mg
12 mL
6 mL
-
>3-5 years
>17.5-25 kg
375 mg
15 mL
7.5 mL
-
> 5-7 years
>25-35 kg
500 mg
20 mL
10 mL
1 tablet
>7-11 years

Children >35 kg and adults

LoE:III389

  • Amoxicillin/clavulanic acid, oral, 875/125 mg 12 hourly for 5 to 10 days             

Severe penicillin allergy: 
ICD-10 Code: Z88.0 

LoE:III390

Children

  • Macrolide, e.g.:
    • Azithromycin, oral, 10 mg/kg daily for 3 days. See: dosing table

Children: >35 kg and adults

  • Macrolide, e.g.:
    • Azithromycin, oral, 500 mg daily for 3 days

Pain:

Children

  • Paracetamol, oral, 10–15 mg/kg/dose 6 hourly when required. See: dosing table

LoE:II391

Adults

  • Paracetamol, oral, 1 g,  4-6 hourly when required
    • Maximum dose: 15 mg/kg/dose
    • Maximum dose: 4 g in 24 hours

For patients with upper respiratory tract congestion, secondary to allergy: (T78.4)

  • Non-sedating antihistamine, oral, e.g.:
    • Cetirizine, oral, 10 mg daily for 10 days

LoE:II392

For management of allergic rhinitis, see: Allergic Rhinitis

REFERRAL

  • Severe pain, fever or vomiting, not responding to treatment after 72 hours (if otoscopy confirmed) or after 24 hours (if otoscopy unconfirmed)
  • Recurrent otitis media
  • Painful swelling behind the ear or tenderness on percussion of the mastoid
  • Suspected meningitis

Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare Level, 2024 Edition

Drugs mentioned

ICD-10 codes

NeoHealth® ID 17693 · updated 4/30/2026