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Pain Management

Approach to pain in the paediatric burns patient

Adapted from Red Cross Hospital Burn Protocol (although these guidelines were developed and are intended for burns patients, they may also be of use in managing paediatric pain from multiple causes).


Objectives for analgesia and sedation
Requirements for procedures
EMLA topical analgesia


Objectives for analgesia and sedation

  • To ensure control of pain, anxiety and movement
  • Enhance safety
  • Minimise patients psychological response: analgesia or anxiolytic with or without amnesia
  • To have a sense of control over the situation and during the procedure
  • To return patient to suitable state for safe discharge = pain under control or pain free

Requirements for procedures (DECIDE WHAT YOU NEED FOR THE PROCEDURE)

  • Analgesia,
  • Amnesia,
  • Sedation,
  • Anxiolysis
  • Or combination of the above

Avoid IM injections in children at all cost as it is traumatic & increases anxiety

All the drug dosages are calculated according to the child’s body weight.

EMLA topical analgesia

  • Topical application: EMLA 5%
    • This is a eutectic mixture of lidocaine 25mg and prilocaine 25mg = 5g cream provides dermal analgesia by the release of lidocaine and prilocaine from the cream into the epidermal and dermal layers of the skin.
    • Useful to prevent pain for IV catheter placement, when time and urgency allows.
  • How to use EMLA:
    • Apply little EMLA on the skin where you intend to put up a drip
    • Cover with a clear adhesive dressing for 20 minutes up to 1 hour for effective analgesia
    • Remove adhesive dressing, wipe away cream and site IV

Note: *Burnshield - meleleuca hydrogel provide analgesia and decrease burn injury


STEP 1

 DRUG
DOSAGE
 FREQUENCY
 SIDE EFFECTS
 COMMENTS
PARACETAMOL
Paracetamol to be co-administered with either valoron drops or morphine
Oral:
Loading dose:
20 mg/kg
Maintenance: 15mg/kg

Rectal:
Loading dose 40mg/kg
Maintenance: 30mg/kg
Maximum daily dose:
  • Neonates: 60mg/kg/24hr
  • Others: 90mg/kg/24 hr

Intravenously (Perfalgan)
15mg/kg/dose

Oral: 4-6 hourly

Rectal: 8 hourly

Intravenously: 6 hourly

Overdose causes liver failure
  • Avoid with impaired liver function
  • No anti-inflammatory effects
  • Good anti-pyretic
  • Can be used together with Opioids and NSAID’s.
  • Available in suppository, suspension /syrup & tablet forms

Warning: Patients with liver conditions: Paracetamol oral dose: 7.5 mg/kg/dose

STEP 2

DRUG
DOSAGE
FREQUENCY
SIDE EFFECTS
COMMENTS
TILIDINE HCL (VALORON)
Oral /Sublingual: 0.5-1mg/kg

6 hourly

As for Opioids
  • Mild sedation
  • constipation nausea &
  • Vomiting, pruritis
  • urinary retention

  • “1 drop per year” under-doses the child
  • Each drop = 2,5mg
  • Very useful analgesic

STEP 3

DRUG
DOSAGE
FREQUENCY
SIDE EFFECTS
COMMENTS
MORPHINE
Oral: 0,3mg/kg/dose

IVI:
Bolus: 
25 –100 mcg/kg/dose

Infusion: 5- 40mcg/kg/hr

Oral: 8-12hrly

IVI:
Bolus: 
4 hourly

Infusion: continuous infusion

  • Nausea Vomiting
  • pruritis
  • urinary retention constipation
  • Respiratory depression
For severe burns, hypovolaemia or hypotension: do not use IM or sc. Give 0.025 – 0.05mg/kg by slow IV bolus. If no IV line, use valoron, 0.5mg/kg/dose po.

Recovery of volume status may cause large doses sub-cut or intramuscular to reach circulation
KETAMINE
Analgesic doses
Oral: 4-6mg/kg/dose
IV: 0.25-0.5mg/kg/dose
Infusion: 0.25-0.5 mg/kg/hour

Repeat dose prn to effect usually min 40-60 min)

continuous

Salivation: (use atropine to reduce secretions: atropine dose 0.01-0.03 mg/kg/dose max. of 2.5mg)
Best used with midazolam (same route as ketamine)

No hallucinations at this dose.

NOTE: Opioid antagonist in case of inadvertent overdose of opioids (Reversal of pain relief). Naloxone (Narcan) 2-4 mcg/kg: IV/sub-cut/IMI (max 10 mcg/kg/dose)

Drugs mentioned

NeoHealth® ID 18552 · updated 9/15/2021