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Papular Urticaria

Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2019 Edition

Description

General measures

Medicine treatment

Referral


L50.8

DESCRIPTION

  • Papular urticaria is a hypersensitivity disorder to insect bites, resulting in recurrent and sometimes chronic itchy papules on exposed areas of the body.
  • An initial lesion appears, usually as a red papule, which may blister, become excoriated, and then heal with hyperpigmentation. Lesions usually occur in crops over several months.
  • Chronic, severe, persistent reactions may be seen in immunocompromised patients, e.g. HIV infection, immunosuppressive therapy, and malnutrition.

GENERAL MEASURES

  • Reduce exposure to insects by treating pets, using mosquito nets and fumigating the household regularly.
  • Use of insect repellents may be helpful.
  • Examine carefully for burrows to rule out scabies.

MEDICINE TREATMENT

New inflamed lesions:

  • Potent topical corticosteroids, e.g.:
    • Betamethasone 0.1%, topical, apply daily for 5 days. 

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For sedation and relief of itch:

  • Chlorphenamine, oral, 4 mg at night as needed in severe cases.

REFERRAL

  • Non-responsive and chronic cases.

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Adult Hospital Level, 2020-2024_Version 1.0_07 November 2024

Chapter 4 Dermatology_4.9.1 Papular Urticaria

Drugs mentioned

ICD-10 codes

NeoHealth® ID 18180 · updated 7/8/2025