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Pneumonia in Adults with Underlying Medical Conditions or >65 Years of Age

Pneumonia in Adults

Medicine Treatment 


J18.0-2/J18.8-9

A chest X-ray should ideally be taken in all patients to confirm the diagnosis. Send one sputum specimen for TB DNA PCR (Xpert® MTB/RIF)to exclude pulmonary tuberculosis.

Common underlying conditions include:

  • Diabetes mellitus
  • HIV infection
  • Cardiac failure
  • COPD
  • Alcoholism
  • Chronic liver disease
  • Chronic kidney disease

Most of these patients will require referral to a doctor.

MEDICINE TREATMENT

Mild pneumonia:

  • Amoxicillin/ clavulanic acid 875/125 mg, oral, 12 hourly for 5 days

Severe Penicillin allergy: 
Z88.0

  • Moxifloxacin, oral, 400 mg daily for 5 days

A follow-up chest X-ray should ideally be taken to ensure resolution of the pneumonia, in patients >50 years of age.

LoE:IIIb36

Click here to access the pdf.


Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare, 2020-4-Version 1.0_16 September 2024

Chapter 17: Respiratory Conditions_17.3. Respiratory infections_17.3.4. Pneumonia_17.3.4.2. Pneumonia in Adults_17.3.4.2.2. Pneumonia in Adults with Underlying Medical Conditions or > 65 Years of Age

Drugs mentioned

ICD-10 codes

NeoHealth® ID 19526 · updated 6/19/2025