Premedication

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Click here to access the Adult Hospital Level Chapter 12: Anaesthesiology and Intensive Care with supporting NEMLC Report_2025-9-Version-1.0_26-February-2026

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• Lorazepam, 1–2 mg, oral, the night before surgery and 1–2 hours preoperatively
  • Use half the dose in the elderly.
  • Duration of action (10-20 hours).
  • Unsuitable for day case surgery.

LoE:III²

• Midazolam, 5-7.5mg oral, one hour preoperatively.
  • Use only in healthy adults < 65 years of age. 
  • Duration of action 1–4 hours.       
  • Suitable for day case surgery.

LoE:III³

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Standard Treatment Guidelines and Essential Medicines List for South Africa, Hospital Level, Adults 2024 Edition